ReviewAging and disease2013
Aging, functional capacity and eccentric exercise training.
Review in Aging and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Increased Dietary Protein Prevent the Suppression of Metabolism and Maintain Anabolic Sensitivity of Bone and Skeletal Muscle During Caloric Restriction?
Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults
Effects of Overground Robot-Assisted Gait Training and Recumbent Bicycle Training on Muscle Characteristics, Falls Efficacy, and Physical Function in Patients With Subacute Stroke-Related Sarcopenia
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Eccentric-Only Versus Concentric-Only Isokinetic Strength Training Effects on Maximal Voluntary Eccentric, Concentric and Isometric Contraction Strength: A Systematic Review and Meta-analysis.Sports medicine - open · 2025Pooled it
- The Health and Functional Benefits of Eccentric versus Concentric Exercise Training: A Systematic Review and Meta-Analysis.Journal of sports science & medicine · 2023Pooled it
- Effects of exercise on neuromuscular junction components across age: systematic review of animal experimental studies.BMC research notes · 2015Pooled it
- Programming and supervision of resistance training leads to positive effects on strength and body composition: results from two randomised trials of community fitness programmes.BMC public health · 2018Trial
- Eccentric versus traditional resistance exercise for older adult fallers in the community: a randomized trial within a multi-component fall reduction program.BMC geriatrics · 2017Trial
- Effects of photobiomodulation on the fatigue level in elderly women: an isokinetic dynamometry evaluation.Lasers in medical science · 2016Trial
- Effects of eccentric-focused and conventional resistance training on strength and functional capacity of older adults.Age (Dordrecht, Netherlands) · 2015Trial
- Resistance exercise with older fallers: its impact on intermuscular adipose tissue.BioMed research international · 2014Trial
- Eccentric cycling for chronic respiratory disease: Does helmet ventilation add value? A randomized controlled trial.Chronic respiratory diseaseTrial
- Gastrocnemius medialis muscle-tendon behavior during eccentric exercise in young and active older adults.GeroScience · 2026Article
- Comparing high-intensity resistance training incorporating periodic eccentric-only exercise with blood flow restriction training in older men: physiological responses and exercise feasibility.European journal of applied physiology · 2026Article
- Effects of Commercial Exergames vs. Traditional Indoor Exercise on Mood in Older Adults: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- Partial bodyweight-supported squats elicit eccentric contraction of the thigh muscles.BMC musculoskeletal disorders · 2026Article
- Eccentric Cycling Improves Motor Learning More Than Concentric Cycling.Scandinavian journal of medicine & science in sports · 2026Article
- Effect of an acute bout of endurance eccentric exercise on exerkines production in healthy males.European journal of applied physiology · 2026Article
- Effects of a multicomponent intervention on body composition and cardiovascular risk factors in women with obesity- a randomized clinical trial.Journal of diabetes and metabolic disorders · 2025Article
- Association of dietary diversity with disability in activities of daily living among older Chinese people: a longitudinal study.BMC geriatrics · 2025Article
- The Clinical Assessment of Eccentric and Concentric Stepping Kinetics has Utility in Older African American Men with Knee Arthritis.Current aging science · 2025Article
- Physical Activity Fragmentation and Falls in Older Adults: Findings From the National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Evolution of documents related to the influence of physical activity and functional capacity throughout the aging process: a bibliometric review.Frontiers in physiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is a multi-factorial process that ultimately induces a decline in our physiological functioning, causing a decreased health-span, quality of life and independence for older adults. Exercise participation is seen as a way to reduce the impact of aging through maintenance of physiological parameters. Eccentric exercise is a model that can be employed with older adults, due to the muscle's ability to combine high muscle force production with a low energy cost. There may however be a risk of muscle damage before the muscle is able to adapt. The first part of this review describes the process of aging and how it reduces aerobic capacity, muscle strength and therefore functional mobility. The second part highlights eccentric exercise and the associated muscle damage, in addition to the repeated bout effect. The final section reviews eccentric exercise interventions that have been completed by older adults with a focus on the changes in functional mobility. In conclusion, eccentric endurance exercise is a potential training modality that can be applied to older adults for improving muscle strength, aerobic capacity and functional ability. However, further research is needed to assess the effects on aerobic capacity and the ideal prescription for eccentric endurance exercise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.