ReviewAging and disease2013
Autonomic Cardiovascular Damage during Post-menopause: the Role of Physical Training.
Review in Aging and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Physical Exercise Effects on Cardiovascular Autonomic Modulation in Postmenopausal Women-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Effects of Physical Exercise on Sexual Function and Quality of Sexual Life Related to Menopausal Symptoms in Peri- and Postmenopausal Women: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Effect of exercise alone and in combination with time-restricted eating on cardiometabolic health in menopausal women.Journal of translational medicine · 2024Trial
- Satellite cell activation and mTOR signaling pathway response to resistance and combined exercise in elite weight lifters.European journal of applied physiology · 2017Trial
- 2025 Update to the Female Athlete Triad Coalition Consensus Statement Part 1: State of the Science and Introduction of a New Adolescent Model.Sports medicine (Auckland, N.Z.) · 2026Review
- Hormonal Atrial Fibrillation: Pathophysiological Mechanisms That Trigger and Sustain the Arrhythmic Circuits.Biomedicines · 2025Review
- Beetroot Supplementation as a Nutritional Strategy to Support Post-Exercise Autonomic Recovery in Postmenopausal Women: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Menopause and its effects on autonomic regulation of blood pressure: Insights and perspectives.Autonomic neuroscience : basic & clinical · 2025Review
- Article
- Sex differences and sex steroids influence on the presentation and severity of cardiovascular autonomic neuropathy of patients with type 1 diabetes.Cardiovascular diabetology · 2023Article
- Impairment on Cardiovascular Autonomic Modulation in Women with Migraine.International journal of environmental research and public health · 2022Article
- Mildly elevated diastolic blood pressure increases subsequent risk of breast cancer in postmenopausal women in the Health Examinees-Gem study.Scientific reports · 2022Article
- Cold Pressor Testing and Sympathetic Nervous System Contribution to Ischemia with No Obstructive Coronary Artery Disease: Results from the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Project.American heart journal plus : cardiology research and practice · 2022Article
- Role of aerobic physical training on cardiac autonomic and morphophysiological dysfunction in hypertensive rats subjected to ovarian hormone deprivation.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- Anxiety as a risk factor in coronary artery disease among young women.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Effects of different exercise interventions on heart rate variability and cardiovascular health factors in older adults: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2021Review
- Important differences between hypertensive middle-aged women and men in cardiovascular autonomic control-a critical appraisal.Biology of sex differences · 2021Article
- Heart Rate Variability and Cardiovascular Fitness: What We Know so Far.Vascular health and risk management · 2021Review
- Beer Polyphenols and Menopause: Effects and Mechanisms-A Review of Current Knowledge.Oxidative medicine and cellular longevity · 2017Review
- Niacin increased glucose, insulin, and C-peptide levels in sedentary nondiabetic postmenopausal women.International journal of women's health · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Menopause is part of the aging process and is characterized by the natural cessation of menstruation; during this time, the production of ovarian hormones, especially estrogen, is sharply reduced. This reduction can cause symptoms and disorders that affect most women and can interfere with their quality of life. Women are also more susceptible to cardiovascular diseases during this period, considering that these ovarian hormones would be associated with a protective effect on the cardiovascular system, by acting at various levels, contributing to the body homeostasis. Among several effects on the cardiovascular system, the ovarian hormones seem to play an important role in the autonomic control of heart rate and blood pressure. A reduction in ovarian hormones causes an autonomic imbalance and increases the risk of cardiovascular diseases. In fact, this increased risk is justified by the key role the autonomic nervous system plays in all cardiac regulatory mechanisms, exerting a tonic and reflexive influence on the main variables of the cardiovascular system. The autonomic system controls various cardiovascular parameters, such as the modulation of heart rate and blood pressure, myocardial contractility and venous capacitance, directly participating in the regulation of cardiac output. Over the years, the standard treatment for menopause symptoms and disorders has been hormone replacement therapy (HRT). However, many studies have indicated the risks of HRT, which justify the need for new non-pharmacological therapies. To this end, physical training, mainly aerobic, has been applied with excellent results on the cardiovascular autonomic nervous system, as it reduces the risk of cardiac diseases and improves the survival rate with direct beneficial effects on the quality of life of these women during the aging process.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.