Evidence map›Paper›PMID 24307888›Full record

ArticleCurrent colorectal cancer reports2013

Honokiol as a Radiosensitizing Agent for Colorectal cancers.

Zhiyun He, Dharmalingam Subramaniam, Zhongtao Zhang, Youcheng Zhang, Shrikant Anant

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current colorectal cancer reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Zhiyun HeDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China ; Department of General Surgery, Second Hospital of Lanzhou, University of Lanzhou, Gansu 730030, China ; Department of Molecular and Integrative Physiology, Kansas City, Kansas, USA.
Dharmalingam Subramaniam
Zhongtao Zhang
Youcheng Zhang
Shrikant Anant
University of Kansas Medical Center · USBeijing Friendship Hospital · CNCapital Medical University · CNLanzhou University Second Hospital · CN

Funding

Dietary Prevention of CancerR01CA109269 · NCI · WASHINGTON UNIVERSITY · PI ANANT, SHRIKANT · 2005 to 2013
$2.7M
RNA Binding Protein CUGBP2 in Intestinal EpitheliumR01DK062265 · NIDDK · WASHINGTON UNIVERSITY · PI ANANT, SHRIKANT · 2002 to 2010
$1.9M
RNA Binding Proteins in CancerR01CA135559 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ANANT, SHRIKANT · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA109269NCI NIH HHS R01 CA135559NIDDK NIH HHS R01 DK062265
6 · The paper itself

Abstract

Radioresistance is a frustrating obstacle for patients with colorectal cancers (CRCs) undergoing radiotherapy. There is an urgent need to find an effective agent to increase the sensitivity of CRCs to radiation. Honokiol, an active compound purified from Magnolia, was found to radiosensitize colorectal cancer cells both

Indexed as

angiogenesiscell cycleNotchSTAT3

Identifiers

PMID24307888
PMCPMC3844429
OpenAlexW2094334988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.