ArticleThe journal of physical chemistry. B2004
Length Dependent Helix-Coil Transition Kinetics of Nine Alanine-Based Peptides.
Article in The journal of physical chemistry. B, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- FitFoldData: A Web-Based Toolkit for Circular Dichroism and Differential Scanning Calorimetry Data Analysis of Protein Thermal Denaturation.ACS omega · 2025Article
- Backbone Modification in a Protein Hydrophobic Core.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Efficient enumeration and visualization of helix-coil ensembles.Biophysical journal · 2024Article
- Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment.eLife · 2022Article
- Energetics and structure of alanine-rich α-helices via adaptive steered molecular dynamics.Biophysical journal · 2021Article
- Photo-initiated rupture of azobenzene micelles to enable the spectroscopic analysis of antimicrobial peptide dynamics.RSC advances · 2020Article
- Interspecies Bombolitins Exhibit Structural Diversity upon Membrane Binding, Leading to Cell Specificity.Biophysical journal · 2019Article
- Exposing the Nucleation Site in α-Helix Folding: A Joint Experimental and Simulation Study.The journal of physical chemistry. B · 2019Article
- Design of a Short Thermally Stable α-Helix Embedded in a Macrocycle.Chembiochem : a European journal of chemical biology · 2018Article
- HyRes: a coarse-grained model for multi-scale enhanced sampling of disordered protein conformations.Physical chemistry chemical physics : PCCP · 2017Article
- Microscopic nucleation and propagation rates of an alanine-based α-helix.Physical chemistry chemical physics : PCCP · 2017Article
- Experimental and Computational Analysis of Protein Stabilization by Gly-to-d-Ala Substitution: A Convolution of Native State and Unfolded State Effects.Journal of the American Chemical Society · 2016Article
- Thermal-triggerd proteinquake leads to disassembly of DegP hexamer as an imperative activation step.Scientific reports · 2014Article
- Effect of interactions with the chaperonin cavity on protein folding and misfolding.Physical chemistry chemical physics : PCCP · 2014Article
- Testing the diffusing boundary model for the helix-coil transition in peptides.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Impact of ion binding on poly-L-lysine (un)folding energy landscape and kinetics.The journal of physical chemistry. B · 2012Article
- Diffusion models of protein folding.Physical chemistry chemical physics : PCCP · 2011Article
- Are Peptides Good Two-State Folders?Journal of chemical theory and computation · 2011Article
- Direct assessment of the α-helix nucleation time.The journal of physical chemistry. B · 2011Article
- Infrared study of the folding mechanism of a helical hairpin: porcine PYY.Biochemistry · 2010Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
It is well-known that end caps and the peptide length can dramatically influence the thermodynamics of the helix-coil transition. However, their roles in determining the kinetics of the helix-coil transition have not been studied extensively and are less well understood. Kinetic Ising models and sequential kinetic models involving barrier crossing via diffusion all predict that the helix formation time depends monotonically on the peptide length with the relaxation time increasing with respect to increasing chain length. Here, we have studied the helix-coil transition kinetics of a series of Ala-based
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