Evidence map›Paper›PMID 24307790›Full record

ReviewWorld journal of gastroenterology2013

Alcoholism and liver disease in Mexico: genetic and environmental factors.

Sonia Roman, Eloy Alfonso Zepeda-Carrillo, Laura Eugenia Moreno-Luna, Arturo Panduro

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Alcoholic Liver Disease.Clinical liver disease · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Interactions betweenNutrients · 2019
    Article
  11. Association of Ambient Air Pollution with Increased Liver Enzymes in Korean Adults.International journal of environmental research and public health · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Development of an in vitro model to test antifibrotic drugs on primary human liver myofibroblasts.Laboratory investigation; a journal of technical methods and pathology · 2016
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sonia RomanSonia Roman, Eloy Alfonso Zepeda-Carrillo, Laura Eugenia Moreno-Luna, Arturo Panduro, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde" and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico.
Eloy Alfonso Zepeda-Carrillo
Laura Eugenia Moreno-Luna
Arturo Panduro
Universidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcoholism and cirrhosis, which are two of the most serious health problems worldwide, have a broad spectrum of clinical outcomes. Both diseases are influenced by genetic susceptibility and cultural traits that differ globally but are specific for each population. In contrast to other regions around the world, Mexicans present the highest drinking score and a high mortality rate for alcoholic liver disease with an intermediate category level of per capita alcohol consumption. Mexico has a unique history of alcohol consumption that is linked to profound anthropological and social aspects. The Mexican population has an admixture genome inherited from different races, Caucasian, Amerindian and African, with a heterogeneous distribution within the country. Thus, genes related to alcohol addiction, such as dopamine receptor D2 in the brain, or liver alcohol-metabolizing enzymes, such as alcohol dehydrogenase class I polypeptide B, cytochrome P450 2E1 and aldehyde dehydrogenase class 2, may vary from one individual to another. Furthermore, they may be inherited as risk or non-risk haplogroups that confer susceptibility or resistance either to alcohol addiction or abusive alcohol consumption and possibly liver disease. Thus, in this era of genomics, personalized medicine will benefit patients if it is directed according to individual or population-based data. Additional association studies will be required to establish novel strategies for the prevention, care and treatment of liver disease in Mexico and worldwide.

Indexed as

Gene-Environment InteractionAlcohol DrinkingAlcoholic BeveragesAlcoholismCultural CharacteristicsGenetic Predisposition to DiseaseHeredityHumansLiver Diseases, AlcoholicMexicoPedigreePrognosisRisk FactorsSocial BehaviorAlcoholAlcohol abuseAlcohol addictionAlcohol dependenceAlcoholic liver cirrhosisAlcoholismAnthropologyGenes

Identifiers

PMID24307790
PMCPMC3848144
OpenAlexW2114675980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.