ReviewFrontiers of medicine2014
Genetic evidence in planar cell polarity signaling pathway in human neural tube defects.
Review in Frontiers of medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- PRICKLE3 protects VANGL proteins from CK1-mediated phosphorylation and RNF43-mediated degradation.Communications biology · 2025Article
- Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation.Open biology · 2024Article
- A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled.PLoS genetics · 2023Article
- Single nucleotide polymorphisms of PCP pathway related genes participate in the occurrence and development of neural tube defect.Molecular genetics & genomic medicine · 2023Article
- The transcriptomic landscape of caudal cell mass in different developmental stages of the chick embryo.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo.Development (Cambridge, England) · 2021Article
- Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway.Italian journal of pediatrics · 2019Article
- Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation.Development (Cambridge, England) · 2018Article
- Genetic contribution of retinoid-related genes to neural tube defects.Human mutation · 2018Article
- Identification of transcripts potentially involved in neural tube closure using RNA sequencing.Genesis (New York, N.Y. : 2000) · 2018Article
- Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects.European journal of human genetics : EJHG · 2018Article
- Association of neural tube defects with gene polymorphisms in one-carbon metabolic pathway.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Unjoined primary and secondary neural tubes: junctional neural tube defect, a new form of spinal dysraphism caused by disturbance of junctional neurulation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?Frontiers in cell and developmental biology · 2017Review
- Variants in TNIP1, a regulator of the NF-kB pathway, found in two patients with neural tube defects.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Temperature Sensitivity of Neural Tube Defects in Zoep Mutants.Zebrafish · 2015Article
- Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway.PloS one · 2015Article
- Junctional neurulation: a unique developmental program shaping a discrete region of the spinal cord highly susceptible to neural tube defects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neural tube defects (NTDs) are a group of birth anomalies having a profound physical, emotional, and financial effects on families and communities. Their etiology is complex, involving environmental and genetic factors that interact to modulate the incidence and severity of the developing phenotype. The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulation and neural tube closure and has been implicated in the pathogenesis of NTDs in animal models and human cohorts. This review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs. These results demonstrate that PCP gene alterations contribute to the etiology of human NTDs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.