ArticlePhotosynthesis research1995
The unusually strong stabilizing effects of glycine betaine on the structure and function of the oxygen-evolving Photosystem II complex.
Article in Photosynthesis research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed, 435 citations in OpenAlex.
- Overexpression ofBiomolecules · 2025Article
- Advances in the Biosynthetic Regulation and Functional Mechanisms of Glycine Betaine for Enhancing Plant Stress Resilience.International journal of molecular sciences · 2025Review
- Systems analysis of long-term heat stress responses in the C4 grass Setaria viridis.The Plant cell · 2025Article
- Proline Promotes Drought Tolerance in Maize.Biology · 2025Article
- Limiting factors in the operation of photosystems I and II in cyanobacteria.Microbial biotechnology · 2024Review
- Plant Adaptation and Tolerance to Heat Stress: Advance Approaches and Future Aspects.Combinatorial chemistry & high throughput screening · 2024Review
- Sensitivity and responses of chloroplasts to salt stress in plants.Frontiers in plant science · 2024Review
- HeterologousInternational journal of molecular sciences · 2023Article
- Improved salt-tolerance of transgenic soybean by stable over-expression of AhBADH gene from Atriplex hortensis.Plant cell reports · 2023Article
- Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light.The Journal of biological chemistry · 2023Article
- Ectomycorrhizal Fungi Modulate Pedunculate Oak's Heat Stress Responses through the Alternation of Polyamines, Phenolics, and Osmotica Content.Plants (Basel, Switzerland) · 2022Article
- ProX from marine Synechococcus spp. show a sole preference for glycine-betaine with differential affinity between ecotypes.Environmental microbiology · 2022Article
- Amelioration Effect of Salicylic Acid Under Salt Stress in Sorghum bicolor L.Applied biochemistry and biotechnology · 2022Article
- Overexpression ofIranian journal of biotechnology · 2022Article
- Glycine betaine increases salt tolerance in maize (Frontiers in plant science · 2022Article
- Exogenous Glycine Betaine Application Improves Freezing Tolerance of Cabbage (Plants (Basel, Switzerland) · 2021Article
- Snowball Earth, population bottleneck andProceedings. Biological sciences · 2021Article
- Morpho-Physiological Testing of NaCl Sensitivity of Tobacco Plants Overexpressing Choline Oxidase Gene.Plants (Basel, Switzerland) · 2021Article
- Metabolic engineering of osmoprotectants to elucidate the mechanism(s) of salt stress tolerance in crop plants.Planta · 2021Review
- Integration of Gas Exchange With Metabolomics: High-Throughput Phenotyping Methods for Screening Biostimulant-Elicited Beneficial Responses to Short-Term Water Deficit.Frontiers in plant science · 2021Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural osmoregulatory substances (osmolytes) allow a wide variety of organisms to adjust to environments with high salt and/or low water content. In addition to their role in osmoregulation, some osmolytes protect proteins from denaturation and deactivation by, for example, elevated temperature and chaotropic compounds. A ubiquitous protein-stabilizing osmolyte is glycine betaine (N-trimethyl glycine). Its presence has been reported in bacteria, in particular cyanobacteria, in animals and in plants from higher plants to algae. In the present review we describe the experimental evidence related to the ability of glycine betaine to enhance and stabilize the oxygen-evolving activity of the Photosystem II protein complexes of higher plants and cyanobacteria. The osmolyte protects the Photosystem II complex against dissociation of the regulatory extrinsic proteins (the 18 kD, 23 kD and 33 kD proteins of higher plants and the 9 kD protein of cyanobacteria) from the intrinsic components of the Photosystem II complex, and it also stabilizes the coordination of the Mn cluster to the protein cleft. By contrast, glycine betaine has no stabilizing effect on partial photosynthetic processes that do not involve the oxygen-evolving site of the Photosystem II complex. It is suggested that glycine betaine might act, in part, as a solute that is excluded from charged surface domains of proteins and also as a contact solute at hydrophobic surface domains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.