ArticleThe Journal of bone and joint surgery. American volume2013
Origin of propionibacterium in surgical wounds and evidence-based approach for culturing propionibacterium from surgical sites.
Article in The Journal of bone and joint surgery. American volume, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cutibacterium Acnes Persists Despite Topical Clindamycin and Benzoyl Peroxide
Effect of Antiseptic Irrigation With 0.05% Chlorhexidine Gluconate (Irrisept) on Incidence of Cutibacterium Acnes in Shoulder Arthroplasty
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it, 165 citations in OpenAlex.
- What is a "periprosthetic shoulder infection"? A systematic review of two decades of publications.International orthopaedics · 2017Pooled it
- Randomized controlled trial of chlorhexidine wash versus benzoyl peroxide soap for home surgical preparation: neither is effective in removing Cutibacterium from the skin of shoulder arthroplasty patients.International orthopaedics · 2020Trial
- Subcutaneous tissue disinfection is more effective than the use of electrocautery in reducingJSES international · 2026Article
- Does fluid irrigation in arthroscopic shoulder biopsy affect sensitivity ofJSES international · 2025Article
- Delayed infection following axillary shoulder incisions.JSES reviews, reports, and techniques · 2025Article
- Resection arthroplasty for deep shoulder infection in a native shoulder with an intact rotator cuff: a salvage option when reverse shoulder arthroplasty is not feasible.Archives of orthopaedic and trauma surgery · 2025Article
- Accuracy of clinical symptoms and nuclear imaging in the diagnosis of infection in revision shoulder arthroplasty.JSES international · 2025Article
- The shoulder microbiome: a systematic review and meta analysis.JSES reviews, reports, and techniques · 2024Review
- Does hydrogen peroxide help mitigate the incidence ofNorth American Spine Society journal · 2024Article
- Impact of postoperative skin disinfection with chlorhexidine on bacterial colonisation following shoulder arthroplasty surgery: a controlled randomised study.Infection prevention in practice · 2024Article
- Dynamics of Cutibacterium repopulation onto the skin surface of the shoulder after chlorhexidine application.International orthopaedics · 2023Article
- Evaluation of the effectiveness of skin preparation methods for the reduction ofShoulder & elbow · 2022Review
- Efficacy of antimicrobial washes before shoulder surgery againstJSES reviews, reports, and techniques · 2022Review
- Occult clavicle osteomyelitis caused by Cutibacterium acnes (C. acnes) after coracoclavicular ligament reconstruction: A case report and review of the literature.International journal of surgery case reports · 2022Article
- Factors associated with failure of surgical revision and IV antibiotics to resolve Cutibacterium periprosthetic infection of the shoulder.International orthopaedics · 2022Article
- RecurrentBMJ case reports · 2021Article
- Is Propionibacterium acnes becoming the most common bacteria in delayed infections following adolescent idiopathic scoliosis surgery?Spine deformity · 2021Article
- Diagnosis of orthopaedic-implant-associated infections caused by slow-growing Gram-positive anaerobic bacteria - a clinical perspective.Journal of bone and joint infection · 2021Review
- The pencil eraser swab technique to quantifyJournal of bone and joint infection · 2021Article
- The management of infected shoulder arthroplasty by two-stage revision.Shoulder & elbow · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo explore the origin of Propionibacterium in surgical wounds and to suggest an optimized strategy for culturing this organism at the time of revision surgery, we studied the presence of this organism on the skin and in the surgical wounds of patients who underwent revision arthroplasty for reasons other than apparent infection.
methodsSpecimens were cultured in broth and on aerobic and anaerobic media. The presence and degree of positivity of Propionibacterium cultures were correlated with sex. The results of dermal and deep cultures were correlated. Times to positivity and the yields of each media type and specimen source were investigated.
resultsPropionibacterium grew in twenty-three of thirty cultures of specimens obtained preoperatively from the unprepared epidermis over the area where a skin incision was going to be made for a shoulder arthroplasty; males had a greater average degree of positivity than females (p < 0.002). Twelve of twenty-one male subjects and zero of twenty female subjects who had cultures of dermal specimens obtained during revision shoulder arthroplasty had positive findings for Propionibacterium (p = 0.0001). Twelve of twenty male subjects and only one of twenty female subjects had positive deep cultures (p = 0.0004). The positivity of dermal cultures for Propionibacterium was significantly associated with the positivity of deep cultures for this organism (p = 0.0001). If Propionibacterium was present in deep tissues, it was likely that it would be recovered by culture if four different specimens were obtained and cultured for a minimum of seventeen days on three different media: aerobic, anaerobic, and broth.
conclusionsBecause the surgical incision of dermal sebaceous glands may be a source of Propionibacterium in deep wounds, strategies for minimizing the risk of Propionibacterium infections may need to be directed at minimizing the contamination of surgical wounds from these bacteria residing in rather than on the skin. Obtaining at least four specimens, observing them for seventeen days, and using three types of culture media optimize the recovery of Propionibacterium at the time of revision surgery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.