Evidence map›Paper›PMID 24306553›Full record

ArticleNeuroradiology2014

Clinical significance of post-interventional cerebral hyperdensities after endovascular mechanical thrombectomy in acute ischaemic stroke.

Omid Nikoubashman, Arno Reich, Mirco Gindullis, Katharina Frohnhofen, Rastislav Pjontek, Marc-Alexander Brockmann, Jörg B Schulz, Martin Wiesmann

Abstract read
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In one paragraph

Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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  18. Hyper-attenuating brain lesions on CT after ischemic stroke and thrombectomy are associated with final brain infarction.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
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  19. Contrast Extravasation versus Hemorrhage after Thrombectomy in Patients with Acute Stroke.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Omid NikoubashmanKlinik für Diagnostische und Interventionelle Neuroradiologie, Uniklinik Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Arno Reich
Mirco Gindullis
Katharina Frohnhofen
Rastislav Pjontek
Marc-Alexander Brockmann
Jörg B Schulz
Martin Wiesmann
Universitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to investigate the clinical significance of post-interventional cerebral hyperdensities (PCHD) after endovascular mechanical thrombectomy in acute ischaemic stroke.

methodsData of 102 consecutive patients who received post-interventional CT scans within 4.5 h after mechanical thrombectomy were analysed retrospectively.

resultsSixty-two of 102 patients (60.8 %) had PCHD on their post-interventional CT scans. The most common site of PCHD was the basal ganglia. PCHD were persisting in 13 of 62 patients (21.0 %), and transient in the remaining 49 patients (79.0 %) within 24 h. Four patients with PCHD and four patients without PCHD suffered from parenchymal haemorrhage. Neither ASA nor Clopidogrel, Tirofiban or rtPA were risk factors for PCHD. Final infarction size was congruent with or bigger than areas of PCHD in 93.3 % of cases in our series.

conclusionPCHD was not a risk factor for parenchymal haemorrhage in our series. The occurrence of PCHD was strongly related to the prior presence of infarction. PCHD was also a strong predictor for final infarction size.

Indexed as

Acute DiseaseAgedBrainBrain IschemiaCerebral HemorrhageFemaleGermanyHumansMaleMechanical ThrombolysisPrevalenceRadiographyRetrospective StudiesRisk FactorsStrokeTreatment Outcome

Identifiers

PMID24306553
OpenAlexW2085386560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.