ArticlePlant cell reports2014
cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots.
Article in Plant cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Exogenous Hormone Treatments Reveal Species-Specific Regulation of Individual Components of Root Architecture and Salt Ion Accumulation in Cultivated and Wild Tomatoes.Plant direct · 2026Article
- Dissecting the ROS signalling component of salinity tolerance: tissue-specific K+/Na+ homeostasis in quinoa and spinach roots.Journal of experimental botany · 2026Article
- panomiX: Investigating mechanisms of trait emergence through multi-omics data integration.Plant phenomics (Washington, D.C.) · 2025Article
- SlALKBH9B is involved in drought-induced flower drop by regulating ethylene production.Horticulture research · 2025Article
- Cadmium toxicity: its' uptake and retaliation by plant defence system and ja signaling.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Review
- Cyclic guanosine monophosphate improves salt tolerance in Solanum lycopersicum.Journal of plant research · 2024Article
- Alleviating the adverse effects of salinity stress on Salicornia persica using sodium nitroprusside and potassium nitrate.BMC plant biology · 2023Article
- BdGUCD1 and Cyclic GMP Are Required for Responses ofInternational journal of molecular sciences · 2022Article
- Root Metabolite Differences in Two Maize Varieties Under Lead (Pb) Stress.Frontiers in plant science · 2021Article
- Induction of Jasmonoyl-Isoleucine (JA-Ile)-DependentPlants (Basel, Switzerland) · 2020Article
- A Salt-Signaling Network Involving Ethylene, Extracellular ATP, Hydrogen Peroxide, and Calcium Mediates KInternational journal of molecular sciences · 2020Article
- The Central Negative Regulator of Flooding Tolerance, the PROTEOLYSIS 6 Branch of the N-degron Pathway, Adversely Modulates Salinity Tolerance inPlants (Basel, Switzerland) · 2020Article
- A brief appraisal of ethylene signaling under abiotic stress in plants.Plant signaling & behavior · 2020Article
- Characterization of tomato protein kinases embedding guanylate cyclase catalytic center motif.Scientific reports · 2020Article
- Ethylene promotes pollen tube growth by affecting actin filament organization via the cGMP-dependent pathway in Arabidopsis thaliana.Protoplasma · 2018Article
- Ethylene Improves Root System Development under Cadmium Stress by Modulating Superoxide Anion Concentration inFrontiers in plant science · 2017Article
- In Search of Enzymes with a Role in 3', 5'-Cyclic Guanosine Monophosphate Metabolism in Plants.Frontiers in plant science · 2016Review
- Analyzing serial cDNA libraries revealed reactive oxygen species and gibberellins signaling pathways in the salt response of Upland cotton (Gossypium hirsutum L.).Plant cell reports · 2015Article
- The Role of Ethylene in Plants Under Salinity Stress.Frontiers in plant science · 2015Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messagecGMP promotes ethylene production and enhances the perception of ethylene. Endogenous ethylene or cGMP accumulation maintains ion homeostasis to enhancing salt resistance. etr1 - 3 is insensitive to cGMP under salt stress. ABSTRACT: In the present study, we presented a signaling network involving ethylene and cGMP in salt resistance pathway of Arabidopsis roots. Results showed that the ethylene-insensitive mutant etr1-3 was more sensitive to salt stress than the wild type (WT). etr1-3 displayed a greater electrolyte leakage, thiobarbituric acid reactive substances and Na(+)/K(+) ratio, but a lower plasma membrane (PM) H(+)-ATPase activity compared to WT under the different NaCl contents. Application of 1-aminocyclopropane-1-carboxylic acid (ACC, an ethylene precursor) or 8-Br-cGMP (the cGMP analog) alleviated NaCl-induced injury by maintaining a lower Na(+)/K(+) ratio and increasing PM H(+)-ATPase activity in WT, but not in etr1-3. Roots treated with 8-Br-cGMP could promote ethylene production and enhance the expression of ACC synthase gene in WT. In addition, the 8-Br-cGMP action in NaCl stress was inhibited by aminooxyacetic acid (an inhibitor of ethylene biosynthesis), but 6-Anilino-5,8-quinolinedione (Ly83583, a guanylate cyclase inhibitor) could not affect ACC action in WT. These results suggest that ethylene functions as a downstream signal of cGMP that stimulates the PM H(+)-ATPase activity, which finally results in regulating ion homeostasis in Arabidopsis tolerance to salt. Moreover, cGMP enhanced the perception of ethylene in Arabidopsis under salt stress, which reversed the salt-induced increase of ETR1 and increased ERF1 at the transcript levels in WT. In a word, cGMP modulates salt resistance pathway of ethylene through regulating biosynthesis and perception of ethylene in Arabidopsis roots.
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