ArticleIndustrial health2014
Dispersion method for safety research on manufactured nanomaterials.
Article in Industrial health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Time-Dependent Dispersion of TiOPolymers · 2026Article
- Chitosan-Based Nanoencapsulation of Mānuka Oil for Periodontal Treatment.International journal of molecular sciences · 2025Review
- Investigating the impact of the dispersion protocol on the physico-chemical identity and toxicity of nanomaterials: a review of the literature with focus on TiOParticle and fibre toxicology · 2025Review
- Effects of engineered nanomaterials on the cardiovascular system.Journal of occupational health · 2025Review
- Adapting the in vitro micronucleus assay (OECD Test Guideline No. 487) for testing of manufactured nanomaterials: recommendations for best practices.Mutagenesis · 2024Article
- Exposure to Benzo[a]pyrene Decreases Noradrenergic and Serotonergic Axons in Hippocampus of Mouse Brain.International journal of molecular sciences · 2023Article
- Effect of the TiONanomaterials (Basel, Switzerland) · 2023Article
- Article
- Ultrasound Study of Magnetic and Non-Magnetic Nanoparticle Agglomeration in High Viscous Media.Materials (Basel, Switzerland) · 2022Article
- Novel Surfactant-Free Water Dispersion Technique of TiONanomaterials (Basel, Switzerland) · 2021Article
- Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats.Nanomaterials (Basel, Switzerland) · 2020Article
- Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles.Particle and fibre toxicology · 2019Article
- Rutile nano-bio-interactions mediate dissimilar intracellular destiny in human skin cells.Nanoscale advances · 2019Article
- Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs.Particle and fibre toxicology · 2018Review
- Article
- Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization.Journal of visualized experiments : JoVE · 2017Article
- Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials.Nature protocols · 2017Article
- Single- and double-walled carbon nanotubes enhance atherosclerogenesis by promoting monocyte adhesion to endothelial cells and endothelial progenitor cell dysfunction.Particle and fibre toxicology · 2016Article
- Titanium Dioxide Particle Type and Concentration Influence the Inflammatory Response in Caco-2 Cells.International journal of molecular sciences · 2016Article
- Zn(II) released from zinc oxide nano/micro particles suppresses vasculogenesis in human endothelial colony-forming cells.Toxicology reports · 2015Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanomaterials tend to agglomerate in aqueous media, resulting in inaccurate safety assessment of the biological response to these substances. The present study searched for suitable dispersion methods for the preparation of nanomaterial suspensions. Titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles were dispersed in a biocompatible dispersion medium by direct probe-type sonicator and indirect cup-type sonicator. Size characterization was completed using dynamic light scattering and transmission electron microscopy. A series of dispersion time and output power, as well as two different particle concentrations were tested. Microscopic contamination of metal titanium that broke away from the tip of the probe into the suspension was found. Size of agglomerated nanoparticles decreased with increase in sonication time or output power. Particle concentration did not show obvious effect on size distribution of TiO2 nanoparticles, while significant reduction of secondary diameter of ZnO was observed at higher concentration. A practicable protocol was then adopted and sizes of well-dispersed nanoparticles increased by less than 10% at 7 d after sonication. Multi-walled carbon nanotubes were also well dispersed by the same protocol. The cup-type sonicator might be a useful alternative to the traditional bath-type sonicator or probe-type sonicator based on its effective energy delivery and assurance of suspension purity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.