Evidence map›Paper›PMID 24305504›Full record

ArticleScientific reports2013

International Chronic Ocular Graft-vs-Host-Disease (GVHD) Consensus Group: proposed diagnostic criteria for chronic GVHD (Part I).

Yoko Ogawa, Stella K Kim, Reza Dana, Janine Clayton, Sandeep Jain, Mark I Rosenblatt, Victor L Perez, Hasanain Shikari, Anjo Riemens, Kazuo Tsubota

2 registry-linked trialsOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 103 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04609345 unknown statusnot on this mapstarted 2020, after this paper: background citation

Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients

TypeobservationalSponsorSanten Pharma Malaysia Sdn BhdRan2020 to 2021Enrolled400ConditionsPrimary Open-angle Glaucoma, Primary Angle-Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigment Dispersion Glaucoma
NCT05170347 recruitingnot on this mapstarted 2021, after this paper: background citation

Ocular Graft-Versus-Host-Disease After Allogeneic Haematopoietic Stem Cell Transplantation: A Territory-Wide Prospective Cohort

Typeobservational_patient_registrySponsorThe University of Hong KongRan2021 to 2028Enrolled500ConditionsGraft Vs Host Disease, Haematological Malignancy, Cancer
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 4 syntheses or guidelines pooled it, 236 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Trial
  6. Bandage Soft Contact Lenses for Ocular Graft-versus-Host Disease.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Trial
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. [Ocular graft versus host disease].Die Ophthalmologie · 2025
    Review
  20. Review

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 3 countries.

Yoko OgawaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Stella K Kim
Reza Dana
Janine Clayton
Sandeep Jain
Mark I Rosenblatt
Victor L Perez
Hasanain Shikari
Anjo Riemens
Kazuo Tsubota
Keio University · JPCornell University · USHarvard University Press · USMassachusetts Eye and Ear Infirmary · USNational Institute of Nursing Research · USThe University of Texas MD Anderson Cancer Center · USUniversity Medical Center Utrecht · NLUniversity of Illinois Chicago · USUniversity of Miami · US

Funding

Immune Mechanisms in Ocular Graft versus Host DiseaseR01EY024484 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LEVY, ROBERT BENJAMIN, PEREZ, VICTOR L · 2014 to 2025
$5.1M
NEI NIH HHS R01 EY024484
6 · The paper itself

Abstract

The International Chronic Ocular GVHD Consensus Group held 4 working meetings to define new diagnostic metrics for chronic ocular graft-versus-host disease (GVHD). After considering the factors currently used to diagnose chronic ocular GVHD, the Consensus Group identified 4 subjective and objective variables to measure in patients following allogeneic hematopoietic stem cell transplantation (HSCT): OSDI, Schirmer's score without anesthesia, corneal staining, and conjunctival injection. Each variable was scored 0-2 or 0-3, with a maximum composite score of 11. Consideration was also given to the presence or the absence of systemic GVHD. On the basis of their composite score and the presence or absence of systemic GVHD, patients were assigned to one of three diagnostic categories: NO, PROBABLE, or DEFINITE ocular GVHD. New diagnostic criteria for chronic ocular GVHD are presented by the Consensus Group. Validation studies are needed to identify the best combination of the proposed metrics to maximize diagnostic sensitivity and specificity.

Indexed as

AdultChronic DiseaseEyeFemaleGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansMaleYoung Adult

Identifiers

PMID24305504
PMCPMC3851919
OpenAlexW2109952435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.