ArticleReproduction, fertility, and development2013
Mammalian fertility preservation through cryobiology: value of classical comparative studies and the need for new preservation options.
Article in Reproduction, fertility, and development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 44 citations in OpenAlex.
- Article
- Long-term preservation of germ cells and gonadal tissues at ambient temperatures.Reproduction & fertility · 2022Review
- Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age?Journal of assisted reproduction and genetics · 2022Article
- Equine ovarian tissue xenografting: impacts of cooling, vitrification, and VEGF.Reproduction & fertility · 2021Article
- Long-term Preservation of Testicular Tissue Integrity and Viability Using Vitrification in the Endangered Black-Footed Ferret (Animals : an open access journal from MDPI · 2020Article
- Rescue of caprine fetal ovaries, vitrification and follicular development after xenotransplantation in two immunodeficient mice models.Animal reproduction · 2020Article
- Heterotopic autotransplantation of ovarian tissue in a large animal model: Effects of cooling and VEGF.PloS one · 2020Article
- Expression of mitofusin 2 in human sperm and its relationship to sperm motility and cryoprotective potentials.Experimental biology and medicine (Maywood, N.J.) · 2018Article
- The mutual benefits of research in wild animal species and human-assisted reproduction.Journal of assisted reproduction and genetics · 2018Review
- Article
- Slow freezing, but not vitrification supports complete spermatogenesis in cryopreserved, neonatal sheep testicular xenografts.PloS one · 2015Article
- Cryopreservation: An Overview of Principles and Cell-Specific Considerations.Cell transplantationReview
- Biobanking efforts and new advances in male fertility preservation for rare and endangered species.Asian journal of andrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Human-related fertility preservation strategies have enormous potential for helping sustain and protect other species, especially to assist managing or 'rescuing' the genomes of genetically valuable individuals, including endangered species. However, wider-scale applications are limited by significant physiological variations among species, as well as a lack of fundamental knowledge of basic reproductive traits and cryosensitivity. Systematic and comparative cryopreservation studies (e.g. on membrane biophysical properties and resilience to freezing temperatures) are required to successfully recover gametes and gonadal tissues after thawing and eventually produce healthy offspring. Such data are currently available for humans and a few laboratory and livestock animals, with virtually all other species, including wildlife, having gone unstudied. Interestingly, there also are commonalities among taxa that allow a protocol developed for one species to provide useful information or guidance for another. However, when a rare animal unexpectedly dies there is no time for a prospective understanding of that species' biophysical traits. Because the odds of success will be much lower in such instances, it is essential that more fundamental studies be directed at more species. But also worthwhile is thinking beyond these systematic characterisations to consider the potential of a 'universal preservation protocol' for animal biomaterials.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.