ArticleMolecular plant pathology2014
Interaction of a Blumeria graminis f. sp. hordei effector candidate with a barley ARF-GAP suggests that host vesicle trafficking is a fungal pathogenicity target.
Article in Molecular plant pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 97 citations in OpenAlex.
- Entanglement of plant immunity and endomembrane trafficking revealed by plant-powdery mildew fungal interactions.The New phytologist · 2026Review
- Sequence-based comparative secretome analysis reveals conserved core effectors and host lineage-specific divergence between monocot- and dicot-associated powdery mildew lineages.Frontiers in plant science · 2026Article
- A powdery mildew core effector protein targets the host endosome tethering complexes HOPS and CORVET in barley.Plant physiology · 2025Article
- Genomic Insights into Disease Resistance in Sunflower (Plants (Basel, Switzerland) · 2024Article
- SDE19, a SEC-dependent effector from 'Candidatus Liberibacter asiaticus' suppresses plant immunity and targets Citrus sinensis Sec12 to interfere with vesicle trafficking.PLoS pathogens · 2024Article
- Leaf rust (Puccinia recondita f. sp. secalis) triggers substantial changes in rye (Secale cereale L.) at the transcriptome and metabolome levels.BMC plant biology · 2024Article
- Article
- Spray-induced gene silencing to identify powdery mildew gene targets and processes for powdery mildew control.Molecular plant pathology · 2023Article
- A Phytophthora capsici RXLR effector manipulates plant immunity by targeting RAB proteins and disturbing the protein trafficking pathway.Molecular plant pathology · 2022Article
- Action Mechanisms of Effectors in Plant-Pathogen Interaction.International journal of molecular sciences · 2022Review
- Infection Strategies and Pathogenicity of Biotrophic Plant Fungal Pathogens.Frontiers in microbiology · 2022Review
- Mutations in a barley cytochrome P450 gene enhances pathogen induced programmed cell death and cutin layer instability.PLoS genetics · 2021Article
- Remote homology clustering identifies lowly conserved families of effector proteins in plant-pathogenic fungi.Microbial genomics · 2021Article
- The vesicular trafficking system component MIN7 is required for minimizing Fusarium graminearum infection.Journal of experimental botany · 2021Article
- Effect of flutianil on the morphology and gene expression of powdery mildew.Journal of pesticide science · 2021Article
- Comparative transcriptome analysis reveals resistant and susceptible genes in tobacco cultivars in response to infection by Phytophthora nicotianae.Scientific reports · 2021Article
- The Powdery Mildew Effector CSEP0027 Interacts With Barley Catalase to Regulate Host Immunity.Frontiers in plant science · 2021Article
- ShNPSN11, a vesicle-transport-related gene, confers disease resistance in tomato to Oidium neolycopersici.The Biochemical journal · 2020Article
- Plant Cells under Attack: Unconventional Endomembrane Trafficking during Plant Defense.Plants (Basel, Switzerland) · 2020Review
- RNA-seq analysis and fluorescence imaging of melon powdery mildew disease reveal an orchestrated reprogramming of host physiology.Scientific reports · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Filamentous phytopathogens, such as fungi and oomycetes, secrete effector proteins to establish successful interactions with their plant hosts. In contrast with oomycetes, little is known about effector functions in true fungi. We used a bioinformatics pipeline to identify Blumeria effector candidates (BECs) from the obligate biotrophic barley powdery mildew pathogen, Blumeria graminis f. sp. hordei (Bgh). BEC1-BEC5 are expressed at different time points during barley infection. BEC1, BEC2 and BEC4 have orthologues in the Arabidopsis thaliana-infecting powdery mildew fungus Golovinomyces orontii. Arabidopsis lines stably expressing the G. orontii BEC2 orthologue, GoEC2, are more susceptible to infection with the non-adapted fungus Erysiphe pisi, suggesting that GoEC2 contributes to powdery mildew virulence. For BEC3 and BEC4, we identified thiopurine methyltransferase, a ubiquitin-conjugating enzyme, and an ADP ribosylation factor-GTPase-activating protein (ARF-GAP) as potential host targets. Arabidopsis knockout lines of the respective HvARF-GAP orthologue (AtAGD5) allowed higher entry levels of E. pisi, but exhibited elevated resistance to the oomycete Hyaloperonospora arabidopsidis. We hypothesize that ARF-GAP proteins are conserved targets of powdery and downy mildew effectors, and we speculate that BEC4 might interfere with defence-associated host vesicle trafficking.
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