Evidence map›Paper›PMID 24304944›Full record

ArticleParasites & vectors2013

Sensitivity of a point of care tick-test for the development of Lyme borreliosis.

Hein Sprong, Arieke Docters van Leeuwen, Manoj Fonville, Margriet Harms, Arnold J van Vliet, Wilfrid van Pelt, José A Ferreira, Cees C van den Wijngaard

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hein SprongCentre for Infectious Disease Control Netherlands, National Institute for Public Health and Environment, Antonie van Leeuwenhoeklaan 9 P,O, Box 1 3720 BA, Bilthoven, The Netherlands. Hein.Sprong@rivm.nl.
Arieke Docters van Leeuwen
Manoj Fonville
Margriet Harms
Arnold J van Vliet
Wilfrid van Pelt
José A Ferreira
Cees C van den Wijngaard
National Institute for Public Health and the Environment · NLWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA commercially available self-test for the detection of Borrelia burgdorferi sensu lato in ticks was evaluated for its ability to predict erythema migrans formation.

findingsThe self-test was performed on 127 Ixodes ricinus from 122 humans that reported tick bites at enrolment and occurrence of symptoms during follow-up. The self-test gave negative results on all the 122 individuals, 14 of whom reported erythema migrans (EM) at follow-up of which 10 were confirmed by their GP. The estimated sensitivity of the self-test for prediction of EM formation is 0% (95% CI: 0%-28%).

conclusionsThis self-test is not suitable for reducing the number needed to treat in a post-exposure prophylaxis setting as it already missed all the obvious early Lyme borreliosis cases.

Indexed as

AnimalsBorrelia burgdorferi GroupHumansIxodesLyme DiseasePoint-of-Care SystemsSensitivity and Specificity

Identifiers

PMID24304944
PMCPMC4235040
OpenAlexW2118024406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.