Evidence map›Paper›PMID 24304585›Full record

ReviewMolecules (Basel, Switzerland)2013

C-4 gem-dimethylated oleanes of Gymnema sylvestre and their pharmacological activities.

Giovanni Di Fabio, Valeria Romanucci, Mauro Zarrelli, Michele Giordano, Armando Zarrelli

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. The metabolic effect ofFrontiers in nutrition · 2023
    Pooled it
  2. Metabolites · 2023
    Article
  3. Article
  4. Article
  5. Plant Leaves Extract Irrigation on Wound Healing in Diabetic Foot Ulcers.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  6. The Reproductive Toxicity Associated withEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  7. Review
  8. Article
  9. HPLC Quantification of Thymoquinone Extracted fromEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  10. Review
  11. Review
  12. Use of Natural Products in Asthma Treatment.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  13. Ultrastructural Changes in Hepatocytes and Chemopreventive Effects of Short-Term Administration ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giovanni Di FabioDepartment of Chemical Sciences, University Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, Napoli 80126, Italy. zarrelli@unina.it.
Valeria Romanucci
Mauro Zarrelli
Michele Giordano
Armando Zarrelli
University of Naples Federico II · ITNational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. This paper aims to summarize the chemical and pharmacological reports on a large group of C-4 gem-dimethylated pentacyclic triterpenoids from Gymnema sylvestre.

Indexed as

AnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsAntiparasitic AgentsGymnema sylvestreHemolysisHumansHypoglycemic AgentsHypolipidemic AgentsMolecular StructureOleanolic AcidPlants, MedicinalTasteAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsAntiparasitic AgentsHypoglycemic AgentsHypolipidemic AgentsOleanolic Acid

Identifiers

PMID24304585
PMCPMC6269971
OpenAlexW2103623643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.