ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2013
Toward semantic modeling of pharmacogenomic knowledge for clinical and translational decision support.
Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The trial behind it
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Who cites it
4 citing papers in PubMed.
- Leveraging a pharmacogenomics knowledgebase to formulate a drug response phenotype terminology for genomic medicine.Bioinformatics (Oxford, England) · 2022Article
- Design and evaluation of a pharmacogenomics information resource for pharmacists.Journal of the American Medical Informatics Association : JAMIA · 2017Article
- Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements.International journal of medical informatics · 2016Article
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Authors and funding
6 authors.
Funding
Abstract
The purpose of this paper is to describe pilot work on a semantic model of the pharmacogenomics information found in drug product labels. The model's development is driven by a series of use cases that we have developed to demonstrate how structured pharmacogenomics information could be more effectively used to support clinical and translational efforts. Using an iterative process, the semantic model was field-tested by five pharmacists, who used it to manually annotate a subset of the sections that the Food and Drug Administration's Table of Pharmacogenomic Biomarkers in Drug Labels cites as containing pharmacogenomics information. The five pharmacists identified a total of 213 pharmacogenomics statements in 29 sections. The model showed the potential to make the unstructured pharmacogenomic information currently written in product labeling more accessible and actionable through structured annotations of pharmacogenomics effects and clinical recommendations.
Identifiers
24303292PMC3814496What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.