Evidence map›Paper›PMID 24303232›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2013

Mining for clinical expertise in (undocumented) order sets to power an order suggestion system.

Jonathan H Chen, Russ B Altman

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Predicting inpatient clinical order patterns with probabilistic topic models vs conventional order sets.Journal of the American Medical Informatics Association : JAMIA · 2017
    Article
  3. Article
  4. DYNAMICALLY EVOLVING CLINICAL PRACTICES AND IMPLICATIONS FOR PREDICTING MEDICAL DECISIONS.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2016
    Article
  5. Data-Mining Electronic Medical Records for Clinical Order Recommendations: Wisdom of the Crowd or Tyranny of the Mob?AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2015
    Article
  6. Automated physician order recommendations and outcome predictions by data-mining electronic medical records.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan H ChenDepartment of Medicine, Stanford University, Stanford, CA 94305, USA.
Russ B Altman

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1RR025744 · NCRR · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2008 to 2011
$22.4M
Text Mining for High-fidelity Curation and Discovery of Gene-drug-phenotype RelationshipsR01LM005652 · NLM · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO · 2000 to 2018
$6.2M
Undergraduate Summer Research Experiences Support for Combining systems biology and structural biology to find new therapeuticsR01GM102365 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO · 2012 to 2021
$3.0M
NCATS NIH HHS UL1 TR001085NCRR NIH HHS UL1 RR025744NIGMS NIH HHS R01 GM102365NIGMS NIH HHS R24 GM061374NLM NIH HHS R01 LM005652
6 · The paper itself

Abstract

Physician orders, the concrete manifestation of clinical decision making, are enhanced by the distribution of clinical expertise in the form of order sets and corollary orders. Conventional order sets are top-down distributed by committees of experts, limited by the cost of manual development, maintenance, and limited end-user awareness. An alternative explored here applies statistical data-mining to physician order data (>330K order instances from >1.4K inpatient encounters) to extract clinical expertise from the bottom-up. This powers a corollary order suggestion engine using techniques analogous to commercial product recommendation systems (e.g., Amazon.com's "Customers who bought this…" feature). Compared to a simple benchmark, the item-based association method illustrated here improves order prediction precision from 13% to 18% and further to 28% by incorporating information on the temporal relationship between orders. Incorporating statistics on conditional order frequency ratios further refines recommendations beyond just "common" orders to those relevant to a specific clinical context.

Identifiers

PMID24303232
PMCPMC3845792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.