Evidence map›Paper›PMID 24303229›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2013

Network analysis of unstructured EHR data for clinical research.

Anna Bauer-Mehren, Paea Lependu, Srinivasan V Iyer, Rave Harpaz, Nicholas J Leeper, Nigam H Shah

Open access · greenAbstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Applications of network analysis to routinely collected health care data: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2018
    Pooled it
  2. Inference of dependency knowledge graph for Electronic Health Records.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Functional evaluation of out-of-the-box text-mining tools for data-mining tasks.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
  7. Identifying phenotypic signatures of neuropsychiatric disorders from electronic medical records.Journal of the American Medical Informatics Association : JAMIA · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anna Bauer-MehrenStanford University, Stanford, CA, USA.
Paea Lependu
Srinivasan V Iyer
Rave Harpaz
Nicholas J Leeper
Nigam H Shah
Stanford University · US

Funding

STANFORD COMPOSITE(RMI)U54HG004028 · NHGRI · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2005 to 2014
$36.2M
NHGRI NIH HHS U54 HG004028
6 · The paper itself

Abstract

In biomedical research, network analysis provides a conceptual framework for interpreting data from high-throughput experiments. For example, protein-protein interaction networks have been successfully used to identify candidate disease genes. Recently, advances in clinical text processing and the increasing availability of clinical data have enabled analogous analyses on data from electronic medical records. We constructed networks of diseases, drugs, medical devices and procedures using concepts recognized in clinical notes from the Stanford clinical data warehouse. We demonstrate the use of the resulting networks for clinical research informatics in two ways-cohort construction and outcomes analysis-by examining the safety of cilostazol in peripheral artery disease patients as a use case. We show that the network-based approaches can be used for constructing patient cohorts as well as for analyzing differences in outcomes by comparing with standard methods, and discuss the advantages offered by network-based approaches.

Identifiers

PMID24303229
PMCPMC3845760
OpenAlexW55193321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.