ArticlePloS one2013
Aortopulmonary collateral flow is related to pulmonary artery size and affects ventricular dimensions in patients after the fontan procedure.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Preoperative myocardial strain, mesenteric resistance, and aortopulmonary collateral flow are associated with pleural effusion duration after fontan completion.Frontiers in pediatrics · 2026Article
- Comparison of Clinical Features and Hemodynamics of Single Ventricle Patients With and Without Interventional Closure of Veno-Venous or Aortopulmonary Collaterals.Journal of cardiovascular development and disease · 2025Article
- Relationship of Aortopulmonary Collaterals and Pulmonary Artery Development During Staged Single Ventricle Reconstruction.Pediatric cardiology · 2025Article
- Systemic-to-pulmonary collateral flow associations with antegrade pulmonary flow in single ventricle patients: insights from cardiac magnetic resonance imaging.Frontiers in cardiovascular medicine · 2024Article
- Basic Concepts and Insights into Aortopulmonary Collateral Arteries in Congenital Heart Diseases.The Indian journal of radiology & imaging · 2023Review
- Collaterals in congenital heart disease: when and how to treat?Cardiovascular diagnosis and therapy · 2023Review
- A Rare Cause of Hemoptysis in West Syndrome-Isolated Aortopulmonary Collaterals in Structurally Normal Heart.The Indian journal of radiology & imaging · 2021Article
- Aortopulmonary Collaterals in Single Ventricle Physiology: Variation in Understanding Occlusion Practice Among Interventional Cardiologists.Pediatric cardiology · 2020Article
- Systemic-to-Pulmonary Collateral Flow Correlates with Clinical Condition Late After the Fontan Procedure.Pediatric cardiology · 2020Article
- Heart failure in single right ventricle congenital heart disease: physiological and molecular considerations.American journal of physiology. Heart and circulatory physiology · 2020Review
- Determination of the Frequency of Right and Left Internal Mammary Artery Embolization in Single Ventricle Patients: A Two-Center Study.Pediatric cardiology · 2018Article
- Where Is the "Optimal" Fontan Hemodynamics?Korean circulation journal · 2017Review
- The Pulmonary Circulation in the Single Ventricle Patient.Children (Basel, Switzerland) · 2017Review
- Improved survival after heart transplant for failed Fontan patients with preserved ventricular function.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2016Article
- Effect of Inhaled Nitric Oxide on Blood Flow Dynamics in Patients After the Fontan Procedure Using Cardiovascular Magnetic Resonance Flow Measurements.Pediatric cardiology · 2016Article
- Decision-Making for Surgery in the Management of Patients with Univentricular Heart.Frontiers in pediatrics · 2015Review
- The clinical role of two-dimensional phase-contrast flow measurements through cardiac magnetic resonance in Fontan patients.Annals of pediatric cardiologyArticle
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAortopulmonary collaterals (APCs) are frequently found in patients with a single-ventricle (SV) circulation. However, knowledge about the clinical significance of the systemic-to-pulmonary shunt flow in patients after the modified Fontan procedure and its potential causes is limited. Accordingly, the aim of our study was to detect and quantify APC flow using cardiovascular magnetic resonance (CMR) and assess its impact on SV volume and function as well as to evaluate the role of the size of the pulmonary arteries in regard to the development of APCs.
methods60 patients (mean age 13.3 ± 6.8 years) after the Fontan procedure without patent tunnel fenestration underwent CMR as part of their routine clinical assessment that included ventricular functional analysis and flow measurements in the inferior vena cava (IVC), superior vena cava (SVC) and ascending aorta (Ao). APC flow was quantified using the systemic flow estimator: (Ao) - (IVC + SVC). Pulmonary artery index (Nakata index) was calculated as RPA + LPA area/body surface area using contrast enhanced MR angiography. The patient cohort was divided into two groups according to the median APC flow: group 1 < 0.495 l/min/m(2) and group 2 > 0.495 l/min/m(2).
resultsGroup 1 patients had significant smaller SV enddiastolic (71 ± 16 vs 87 ± 25 ml/m(2); p=0.004) and endsystolic volumes (29 ± 11 vs 40 ± 21 ml/m(2); p=0.02) whereas ejection fraction (59 ± 9 vs 56 ± 13%; p=0.38) differed not significantly. Interestingly, pulmonary artery size showed a significant inverse correlation with APC flow (r=-0.50, p=0.002).
conclusionsVolume load due to APC flow in Fontan patients affected SV dimensions, but did not result in an impairment of SV function. APC flow was related to small pulmonary artery size, suggesting that small pulmonary arteries represent a potential stimulus for the development of APCs.
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