Evidence map›Paper›PMID 24302467›Full record

ArticleLab on a chip2014

Oxygen levels in thermoplastic microfluidic devices during cell culture.

Christopher J Ochs, Junichi Kasuya, Andrea Pavesi, Roger D Kamm

Abstract read
In one paragraph

Article in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Dynamics of nanoparticles in a 3D breathing lung-on-a-chip.Drug delivery and translational research · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Frontiers in bioengineering and biotechnology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher J OchsSingapore MIT Alliance for Research and Technology, BioSystems and Micromechanics, 1 CREATE Way, #04-13/14 Enterprise Wing, Singapore 138602, Singapore.
Junichi Kasuya
Andrea Pavesi
Roger D Kamm

Funding

Microfluidic 3D Assays for Metastatic CancerR33CA174550 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KAMM, ROGER D · 2013 to 2015
$1.1M
NCI NIH HHS 1R33CA174550NCI NIH HHS R33 CA174550
6 · The paper itself

Abstract

We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels. Conditions are determined that provide adequate oxygen supply to two cell types, hepatocytes and endothelial cells, either by diffusion through the plastic device, or by supplying a low flow rate of medium.

Indexed as

Cells, CulturedHepatocytesHumansHuman Umbilical Vein Endothelial CellsMicrofluidic Analytical TechniquesOxygenPolymersSulfitesOxygenPolymerssodium sulfiteSulfites

Identifiers

PMID24302467
PMCPMC4305448

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.