Evidence map›Paper›PMID 24301290›Full record

ReviewJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2014

Impact of particulate matter exposition on the risk of ischemic stroke: epidemiologic evidence and putative mechanisms.

Daniel von Bornstädt, Alexander Kunz, Matthias Endres

Abstract readReview
In one paragraph

Review in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel von Bornstädt1] Department of Neurology Charité-Universitätsmedizin Berlin, Berlin, Germany [2] Center for Stroke Research Berlin Charité-Universitätsmedizin Berlin, Berlin, Germany [3] Neurovascular Research Laboratory, Radiology and Neurology-Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Alexander Kunz1] Department of Neurology Charité-Universitätsmedizin Berlin, Berlin, Germany [2] Center for Stroke Research Berlin Charité-Universitätsmedizin Berlin, Berlin, Germany.
Matthias Endres1] Department of Neurology Charité-Universitätsmedizin Berlin, Berlin, Germany [2] Center for Stroke Research Berlin Charité-Universitätsmedizin Berlin, Berlin, Germany [3] Neurocure-Cluster of Excellence Charité-Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ambient particulate matter (PM) pollution is estimated to be responsible for 3.2 million deaths annually worldwide. Although many studies have demonstrated PM as a serious risk factor for cardiovascular diseases, less is known on its association with cerebrovascular events. Over the last decade, however, an increasing number of studies have provided data showing a relationship between PM exposure and ischemic stroke (IS). In this article, we will report on existing epidemiologic findings for an association between PM exposure and IS based on a systemic literature search. Thus, despite inconsistencies in the results, currently available data suggest that PM exposure is a risk factor for IS, especially in patients with preexisting illnesses. With regards to the mechanisms leading to PM-dependent vascular damage, in particular proinflammatory, prooxidative, as well as proatherogenic pathways have been suggested to be involved. Notably, to date there is only one study published, which demonstrates the influence of PM exposure on cerebrovascular function. We will discuss reasonable approaches for future neurovascular research in this field.

Indexed as

Brain IschemiaStrokeHumansParticulate MatterRisk FactorsParticulate Matter

Identifiers

PMID24301290
PMCPMC3915219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.