ArticleJournal of clinical and diagnostic research : JCDR2013
A study of serum malondialdehyde and cytokine in tuberculosis patients.
Article in Journal of clinical and diagnostic research : JCDR, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Molecular Interplay of Brucellosis and Tuberculosis: Insights into Telomere Biology, Oxidative Stress, and Drug Resistance Mechanisms.Diseases (Basel, Switzerland) · 2026Review
- Interplay between Pro-inflammatory Mediators and Oxidative Stressinvolved Recurrent Chronic Heart Failure in Elderly Patients with Coronary Stents.Current medicinal chemistry · 2025Article
- Oxidative Stress and Trace Elements in Pulmonary Tuberculosis Patients During 6 Months Anti-tuberculosis Treatment.Biological trace element research · 2021Article
- Oxidative Stress Markers in Tuberculosis and HIV/TB Co-Infection.Journal of clinical and diagnostic research : JCDR · 2017Article
- Predicting disease onset in clinically healthy people.Interdisciplinary toxicology · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTuberculosis (TB) is a common and a deadly infectious disease which is caused by Mycobacterium tuberculi. Inflammatory cytokines play an important role during the course of the disease and they may be responsible for tissue damage which is caused by lipid peroxidation.
methodThe present study was conducted in the Department of Biochemistry and patients were selected from Department of TB and Chest Sri Aurobindo Institute of Medical Sciences and also from Manorama Raje Tuberculosis Hospital, Indore. 32 healthy controls and 35 pulmonary TB patients were compared initially for their serum Malondialdehyde (MDA) and tumour necrosis factor alpha (TNF α) levels. Serum TNF α and MDA levels were correlated.
resultTNF α and MDA levels in serum were significantly increased (p<0.001) in pulmonary tuberculosis patients as compared to those of controls. Increased Serum TNF α was positively correlated to MDA levels and it was found to be statistically not significant (correlation coefficient r =0.282,p> 0.05 ).
conclusionThe present study supports the view that there may be a link between lipid peroxidation and cytokine response and relative roles of cytokines and lipid peroxidation in the pathogenesis of tuberculosis.
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