Evidence map›Paper›PMID 24298396›Full record

ArticleBiomedical optics express2013

Handheld simultaneous scanning laser ophthalmoscopy and optical coherence tomography system.

Francesco Larocca, Derek Nankivil, Sina Farsiu, Joseph A Izatt

Abstract read
In one paragraph

Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  6. Article
  7. Article
  8. High-resolutionBiomedical optics express · 2024
    Article
  9. Article
  10. Robotic Optical Coherence Tomography of Human Subjects with Posture-Invariant Head and Eye Alignment in Six Degrees of Freedom.... International Symposium on Medical Robotics. International Symposium on Medical Robotics · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. A review of low-cost and portable optical coherence tomography.Progress in biomedical engineering (Bristol, England) · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. First Clinical Application of Low-Cost OCT.Translational vision science & technology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francesco LaroccaDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Derek Nankivil
Sina Farsiu
Joseph A Izatt

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Ophthalmic Imaging Using Adaptive Optics and OCTR01EY014743 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI WERNER, JOHN S · 2003 to 2012
$10.4M
Portable Motion Compensated SDOCT System for Imaging Young ChildrenR21EY021321 · NEI · DUKE UNIVERSITY · PI FARSIU, SINA, IZATT, JOSEPH A · 2012 to 2013
$404k
NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY014743NEI NIH HHS R21 EY021321
6 · The paper itself

Abstract

Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) are widely used retinal imaging modalities that can assist in the diagnosis of retinal pathologies. The combination of SLO and OCT provides a more comprehensive imaging system and a method to register OCT images to produce motion corrected retinal volumes. While high quality, bench-top SLO-OCT systems have been discussed in the literature and are available commercially, there are currently no handheld designs. We describe the first design and fabrication of a handheld SLO/spectral domain OCT probe. SLO and OCT images were acquired simultaneously with a combined power under the ANSI limit. High signal-to-noise ratio SLO and OCT images were acquired simultaneously from a normal subject with visible motion artifacts. Fully automated motion estimation methods were performed in post-processing to correct for the inter- and intra-frame motion in SLO images and their concurrently acquired OCT volumes. The resulting set of reconstructed SLO images and the OCT volume were without visible motion artifacts. At a reduced field of view, the SLO resolved parafoveal cones without adaptive optics at a retinal eccentricity of 11° in subjects with good ocular optics. This system may be especially useful for imaging young children and subjects with less stable fixation.

Indexed as

(080.3620) Lens system design(110.4153) Motion estimation and optical flow(110.4500) Optical coherence tomography(170.0110) Imaging systems(170.4460) Ophthalmic optics and devices(170.4470) Ophthalmology(170.5755) Retina scanning

Identifiers

PMID24298396
PMCPMC3829529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.