Evidence map›Paper›PMID 24298299›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2013

Mechanisms of Gadographene-Mediated Proton Spin Relaxation.

Andy H Hung, Matthew C Duch, Giacomo Parigi, Matthew W Rotz, Lisa M Manus, Daniel J Mastarone, Kevin T Dam, Colton C Gits, Keith W Macrenaris, Claudio Luchinat and 2 more

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Functional nanoparticles for magnetic resonance imaging.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2016
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andy H HungDepartment of Chemistry, Molecular Biosciences, Neurobiology, Biomedical Engineering, and Radiology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, United States.
Matthew C Duch
Giacomo Parigi
Matthew W Rotz
Lisa M Manus
Daniel J Mastarone
Kevin T Dam
Colton C Gits
Keith W Macrenaris
Claudio Luchinat
Mark C Hersam
Thomas J Meade

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Theranostic Magnetic Nanostructures for the Molecular Imaging of CancerU54CA151880 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLOSCHAK, GAYLE E. · 2010 to 2014
$11.5M
q-Modulated Magnetic Resonance Imaging Contrast AgentsR01EB005866 · NIBIB · NORTHWESTERN UNIVERSITY · PI MEADE, THOMAS J · 2005 to 2013
$2.2M
Steroid-Based Contrast Agents for Magnetic Resonance Imaging of Endocrine DiseaseR01EB014806 · NIBIB · NORTHWESTERN UNIVERSITY · PI MEADE, THOMAS J · 2012 to 2015
$1.4M
NCI NIH HHS P30 CA060553NCI NIH HHS U54 CA151880NIBIB NIH HHS R01 EB005866NIBIB NIH HHS R01 EB014806
6 · The paper itself

Abstract

Gd(III) associated with carbon nanomaterials relaxes water proton spins at an effectiveness that approaches or exceeds the theoretical limit for a single bound water molecule. These Gd(III)-labeled materials represent a potential breakthrough in sensitivity for Gd(III)-based contrast agents used for magnetic resonance imaging (MRI). However, their mechanism of action remains unclear. A gadographene library encompassing GdCl

Indexed as

gadoliniumgraphenegraphene oxidemodified Florence NMRD programrelaxivity

Identifiers

PMID24298299
PMCPMC3843495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.