ArticleDegenerative neurological and neuromuscular disease2012
Deep brain stimulation for the treatment of Parkinson's disease: efficacy and safety.
Article in Degenerative neurological and neuromuscular disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Effect of levodopa-carbidopa intestinal gel on dyskinesia in advanced Parkinson's disease patients.Movement disorders : official journal of the Movement Disorder Society · 2016Trial
- Neuroprotective Efficacy and Complementary Treatment with Medicinal Herbs: A Comprehensive Review of Recent Therapeutic Approaches in Epilepsy Management.CNS & neurological disorders drug targets · 2025Review
- Metallic Nanoparticles Applications in Neurological Disorders: A Review.International journal of biomaterials · 2025Review
- The Effects ofNutrients · 2023Review
- Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation.Neuron · 2021Article
- Identification of arthropathy and myopathy of the temporomandibular syndrome by biomechanical facial features.Biomedical engineering online · 2020Article
- Factors Associated With Dyskinesia in Parkinson's Disease in Mainland China.Frontiers in neurology · 2019Article
- Design of a novel stimulation system with time-varying paradigms for investigating new modes of high frequency stimulation in brain.Biomedical engineering online · 2018Article
- Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases.Cold Spring Harbor perspectives in biology · 2018Review
- [High frequency stimulations change the phase-locking relationship between neuronal firing and the rhythms of field potentials].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Article
- Towards a Better Treatment Option for Parkinson's Disease: A Review of Adult Neurogenesis.Neurochemical research · 2016Review
- Drug Delivery Systems for Imaging and Therapy of Parkinson's Disease.Current neuropharmacology · 2016Review
- Deep brain stimulation for the treatment of resistant hypertension.Current hypertension reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Deep brain stimulation (DBS) surgery has become increasingly utilized in the treatment of advanced Parkinson's disease. Over the past decade, a number of studies have demonstrated that DBS is superior to best medical management in appropriately selected patients. The primary targets for DBS in Parkinson's disease include the subthalamic nucleus and the internal segment of the globus pallidus, both of which improve the cardinal motor features in Parkinson's disease. Recent randomized studies have revealed that both targets are similarly effective in treating the motor symptoms of Parkinson's disease, but emerging evidence suggests that the globus pallidus may be the preferred target in many patients, based on differences in nonmotor outcomes. Here, we review appropriate patient selection, and the efficacy and safety of DBS therapy in Parkinson's disease. Best outcomes are achieved if the problems of the individual patient are considered when evaluating surgical candidates and considering whether the subthalamic nucleus or the globus pallidus internus should be targeted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.