ArticleJournal of neurovirology2013
Peripheral neuropathy in ART-experienced patients: prevalence and risk factors.
Article in Journal of neurovirology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sensory neuropathy and associated factors among patients living with human immuno-deficiency virus in Africa: a systematic review and meta-analysis.Virology journal · 2025Pooled it
- Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial.Journal of neurovirology · 2016Trial
- Comprehensive analysis of spinal cord inflammatory factors in HIV Tat-induced neuropathy in mice.Neuroscience · 2026Article
- Elevated Biomarkers of Inflammation and Vascular Dysfunction Are Associated with Distal Sensory Polyneuropathy in People with HIV.International journal of molecular sciences · 2024Article
- Peripheral Neuropathy in Virologically Suppressed People Living with HIV: Evidence from the PIVOT Trial.Viruses · 2023Article
- HIV-associated painful neuropathy: where are we?Arquivos de neuro-psiquiatria · 2022Article
- Long-term case-fatality rate of nontuberculous mycobacterial disease in people living with HIV.Infectious diseases of poverty · 2022Article
- Nanodelivery of antiretroviral drugs to nervous tissues.Frontiers in pharmacology · 2022Review
- HIV-related Neuropathy: Pathophysiology, Treatment and Challenges.Journal of neurology and experimental neuroscience · 2021Article
- Strength exercise for balance and gait in HIV-associated distal symmetrical polyneuropathy: A randomised controlled trial.Southern African journal of HIV medicine · 2021Article
- Conditional expression of HIV-1 tat in the mouse alters the onset and progression of tonic, inflammatory and neuropathic hypersensitivity in a sex-dependent manner.European journal of pain (London, England) · 2020Article
- Evidence for a novel subcortical mechanism for posterior cingulate cortex atrophy in HIV peripheral neuropathy.Journal of neurovirology · 2020Article
- Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers.Brain, behavior, & immunity - health · 2020Article
- Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice.Scientific reports · 2019Article
- Dissociable Contributions of Precuneus and Cerebellum to Subjective and Objective Neuropathy in HIV.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2019Article
- Peripheral neuropathy in patients with human immunodeficiency viral infection at a tertiary hospital in Ghana.Journal of neurovirology · 2019Article
- Chronic Distal Sensory Polyneuropathy Is a Major Contributor to Balance Disturbances in Persons Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2019Article
- Article
- SIV-Induced Immune Activation and Metabolic Alterations in the Dorsal Root Ganglia During Acute Infection.Journal of neuropathology and experimental neurology · 2019Article
- HIV-associated sensory polyneuropathy and neuronal injury are associated with miRNA-455-3p induction.JCI insight · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Peripheral neuropathy (PN) is a common neurological complication of HIV infection that has debilitating effects on quality of life. While there has been a comprehensive evaluation of the prevalence of neuropathic signs/symptoms and risk factors (RFs) for PN or symptomatic PN (SPN) with initiation of combination antiretroviral therapy (cART) in ART-naïve patients, similar evaluation in ART-experienced patients is limited. This study investigated the prevalence and RFs for PN/SPN in ART-experienced patients enrolled in clinical salvage therapy studies. Between February 2000 and June 2007, 522 ART-experienced participants who experienced virologic failure with a prior regimen and started new regimens were followed longitudinally and annually screened for signs and symptoms of PN. Rates of PN/SPN at 3 years since parent study entry were 52.8 and 24.0 %, respectively. Aging, taller height, protease inhibitor use, and female sex were significant RFs for PN/SPN. The use of statin drugs was significantly associated with lower odds of SPN, and it may prevent progression from no SPN to SPN.
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Registered trials
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