Evidence map›Paper›PMID 24297325›Full record

ReviewLung2014

Airway protective mechanisms.

Teresa Pitts

Open access · greenAbstract readReview
In one paragraph

Review in Lung, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Serotonin therapies for opioid-induced disordered swallow and respiratory depression.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Impact of volume and rate of milk delivery on coordination of respiration and swallowing in infant pigs.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Presbyphagia: Dysphagia in the elderly.World journal of clinical cases · 2023
    Review
  20. Deglutition and the Regulation of the Swallow Motor Pattern.Physiology (Bethesda, Md.) · 2023 · on this map
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Teresa PittsDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, PO Box 100144, Gainesville, FL, 32610-0144, USA, tepitts@ufl.edu.
University of Florida · US

Funding

Regulation of Airway Protective BehaviorsR00HL111215 · NHLBI · UNIVERSITY OF LOUISVILLE · PI PITTS, TERESA G · 2015 to 2017
$731k
Regulation of Airway Protective BehaviorsK99HL111215 · NHLBI · UNIVERSITY OF FLORIDA · PI PITTS, TERESA G · 2013 to 2014
$267k
NHLBI NIH HHS K99 HL111215NHLBI NIH HHS R00 HL111215
6 · The paper itself

Abstract

Cough and swallow are highly coordinated reflex behaviors whose common purpose is to protect the airway. The pharynx is the common tube for air and food/liquid movement from the mouth into the thorax, has been largely overlooked, and is potentially seen as just a passive space. The thyropharyngeus muscle responds to cough inducing stimuli to prepare a transient holding area for material that has been removed from the subglottic airway. The cricopharyngeus muscle participates with the larynx to ensure regulation of pressure when a bolus/air is moving from the upper airway through to the thorax (i.e., inspiration or swallow) or the reverse (i.e., expiration reflex or vomiting). These vital mechanisms have not been evaluated in clinical conditions but could be impaired in many neurodegenerative diseases, leading to aspiration pneumonia. These newly described airway protective mechanisms need further study, especially in healthy and pathologic human populations.

Indexed as

DeglutitionAnimalsCoughHumansLaryngeal NervesLarynxPharynxPneumonia, AspirationReflexTrachea

Identifiers

PMID24297325
PMCPMC3920746
OpenAlexW2035421996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.