ArticleJournal of biosciences2013
Maternal hormonal interventions as a risk factor for Autism Spectrum Disorder: an epidemiological assessment from India.
Article in Journal of biosciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Neuropsychiatric disorders in children of mothers with polycystic ovary syndrome: a systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- A systematic review and meta-analysis of the association between maternal polycystic ovary syndrome and neuropsychiatric disorders in children.Translational psychiatry · 2021Pooled it
- Maternal polycystic ovarian syndrome in autism spectrum disorder: a systematic review and meta-analysis.Molecular psychiatry · 2019Pooled it
- Effects of maternal exposure to exogenous progesterone during pregnancy on offspring neurodevelopment.BMC pediatrics · 2025Observational
- Review
- Androgens Tend to Be Higher, but What about Altered Progesterone Metabolites in Boys and Girls with Autism?Life (Basel, Switzerland) · 2022Article
- Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring.Frontiers in endocrinology · 2022Article
- Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder.Biological psychiatry · 2021Article
- Infertility treatment and autism risk using the Modified Checklist for Autism in Toddlers (M-CHAT).Human reproduction (Oxford, England) · 2020Article
- Resveratrol in Autism Spectrum Disorders: Behavioral and Molecular Effects.Antioxidants (Basel, Switzerland) · 2020Review
- Prenatal, perinatal, and neonatal risk factors of autism spectrum disorder.Pediatric research · 2018Article
- Prenatal Progestin Exposure Is Associated With Autism Spectrum Disorders.Frontiers in psychiatry · 2018Article
- Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation.Molecular autism · 2018Article
- Are Attributes of Pregnancy and the Delivery Room Experience Related to Development of Autism? A Review of the Perinatal and Labor Risk Factors and Autism.International scholarly research notices · 2014Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Globalization and women empowerment have led to stressful life among Indian women. This stress impairs women's hormonal makeup and menstrual cycle, leading to infertility. National Family Health Survey-3 (NFHS-3) reports a decline in fertility status in India, indicating a rise in various infertility treatments involving hormonal interventions. No studies are available from India on the risk association link between maternal hormonal treatments and ASD. Hence, this study explores the association of maternal hormonal interventions with risk for ASD. Parents of 942 children (471 ASD and 471 controls) across 9 cities in India participated in the questionnaire-based study. The questionnaire was pilot tested and validated for its content and reliability as a psychometric instrument. Data collection was done at 70 centres through direct interaction with parents and with the help of trained staff. Statistical analysis of data was carried out using SAS 9.1.3. Out of the 471 ASD cases analysed, 58 mothers had undergone hormonal interventions (12.3 percent) while there were only 22 mothers among controls who underwent hormonal interventions (4.6 percent). According to logistic regression analysis maternal hormonal intervention (OR=2.24) was a significant risk factor for ASD.
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Registered trials
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