Evidence map›Paper›PMID 24296629›Full record

ReviewNature reviews. Nephrology2014

Elderly patients with CKD--dilemmas in dialysis therapy and vascular access.

Tushar J Vachharajani, Louise M Moist, Marc H Glickman, Miguel A Vazquez, Kevan R Polkinghorne, Charmaine E Lok, Timmy C Lee

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07649083 (Comparison of Tunneled Cuffed Dialysis Catheters Versus Arteriovenous Fistulae in Elderly or Multimorbid Patients), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07649083 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Tunneled Cuffed Dialysis Catheters Versus Arteriovenous Fistulae in Elderly or Multimorbid Patients

TypeinterventionalSponsorMedical University of ViennaRan2026 to 2030Enrolled220ConditionsEnd Stage Renal Failure, Hemodialysis, Vascular Access, Fistulas Arteriovenous, Haemodialysis ComplicationArmsTunneled cuffed catheter (TCC) will be implanted for chronic haemodialysis treatment, Arteriovenous fistula creation for chronic haemodialysis treatment
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Vascular access placement and mortality in elderly incident hemodialysis patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020
    Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Engagement in decision-making and patient satisfaction: a qualitative study of older patients' perceptions of dialysis initiation and modality decisions.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2017
    Article
  11. Review
  12. Article
  13. Relationship Between Age and Pre-End Stage Renal Disease Care in Elderly Patients Treated with Maintenance Hemodialysis.Nephrology nursing journal : journal of the American Nephrology Nurses' Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tushar J VachharajaniDivision of Nephrology, W. G. (Bill) Hefner Veterans Affairs Medical Center, 1601 Brenner Avenue, Salisbury, NC 28144, USA.
Louise M MoistKidney Clinical Research Unit, Division of Nephrology, Schulich School of Medicine and Dentistry, Victoria Hospital, Canada.
Marc H GlickmanDepartment of Vascular Surgery, Eastern Virginia Medical School, USA.
Miguel A VazquezDivision of Nephrology, University of Texas Southwestern Medical Center, USA.
Kevan R PolkinghorneDepartment of Medicine and Department of Nephrology, Monash Medical Center & Monash University, Australia.
Charmaine E LokDivision of Nephrology, Department of Medicine, Toronto General Hospital and University of Toronto, Canada.
Timmy C LeeDivision of Nephrology, University of Alabama at Birmingham, USA.

Funding

Novel Biological Markers in Impaired Arteriovenous Fistula MaturationK23DK083528 · NIDDK · UNIVERSITY OF CINCINNATI · PI LEE, TIMMY C · 2009 to 2013
$843k
NIDDK NIH HHS K23 DK083528
6 · The paper itself

Abstract

The population of elderly patients with end-stage renal disease (ESRD) is growing rapidly worldwide. The high prevalence of comorbidities, limited life expectancy and complex quality of life issues associated with this population pose substantial challenges for clinicians in terms of clinical decision-making and providing optimal care. The first dilemma encountered in the management of an elderly patient with ESRD is deciding whether to initiate renal replacement therapy and, if so, selecting the most-suitable dialysis modality. Planning vascular access for haemodialysis is associated with additional challenges. Several clinical practice guidelines recommend an arteriovenous fistula, rather than a central venous catheter or arteriovenous graft, as the preferred access for maintenance haemodialysis therapy. However, whether this recommendation is applicable to elderly patients with ESRD and a limited life expectancy is unclear. Selection and planning of the most appropriate vascular access for an elderly patient with ESRD requires careful consideration of several factors and ultimately should lead to an improvement in the patient's quality of life.

Indexed as

Catheters, IndwellingDecision MakingRenal DialysisAgedHumansKidney Failure, Chronic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.