Evidence map›Paper›PMID 24296308›Full record

ArticleJournal of the Formosan Medical Association = Taiwan yi zhi2014

Utilization of emergency medical service increases chance of thrombolytic therapy in patients with acute ischemic stroke.

Ming-Ju Hsieh, Sung-Chun Tang, Wen-Chu Chiang, Kuang-Yu Huang, Anna Marie Chang, Patrick Chow-In Ko, Li-Kai Tsai, Jiann-Shing Jeng, Matthew Huei-Ming Ma

Abstract read
In one paragraph

Article in Journal of the Formosan Medical Association = Taiwan yi zhi, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. [Effects of emergency medical service on prognosis of ischemic stroke patients treated with intravenous thrombolysis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019
    Article
  7. Review
  8. Strategies for streamlining emergency stroke care.Current neurology and neuroscience reports · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Ju HsiehDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Sung-Chun TangStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
Wen-Chu ChiangDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Kuang-Yu HuangStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
Anna Marie ChangDepartment of Emergency Medicine, Oregon Health and Science University, Portland, OR, USA.
Patrick Chow-In KoDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Li-Kai TsaiStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
Jiann-Shing JengStroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: jsjeng@ntu.edu.tw.
Matthew Huei-Ming MaDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: matthew@ntu.edu.tw.

Funding

Oregon Multidisciplinary Training Program in Emergency Medicine Clinical ResearchK12HL108974 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NEWGARD, CRAIG D. · 2011 to 2015
$3.8M
NHLBI NIH HHS K12 HL108974
6 · The paper itself

Abstract

background/purposeTo determine whether utilization of emergency medical service (EMS) can increase use and expedite delivery of the thrombolytic therapy in acute ischemic stroke patients.

methodsWe analyzed consecutive patients presenting to the emergency department (ED) with an ischemic stroke within 72 hours of symptom onset from a prospective stroke registry. Variables associated with early ED arrival (within 3 hours of stroke onset) and administration of intravenous thrombolytic therapy were analyzed.

resultsFrom January 1, 2010 to July 31, 2011, there were 1081 patients (62.3% men, age 69.6 ± 13 years) included in this study. Among them, 289 (26.7%) arrived in the ED within 3 hours, and 88 (8.1%) received thrombolytic therapy. Patients who arrived at the ED by EMS (n = 279, 25.8%) were independently associated with earlier ED arrival (adjusted odds ratio = 3.68, 95% confidence interval = 2.54-5.33), and higher chance of receiving thrombolytic therapy (adjusted odds ratio = 3.89, 95% confidence interval = 1.86-8.17). Furthermore, utilization of EMS significantly decreased onset-to-needle time by 26 minutes in patients receiving thrombolytic therapy.

conclusionUtilization of EMS can not only help acute ischemic stroke patients in early presentation to ED, but also effectively facilitate thrombolytic therapy and shorten the onset-to-needle time.

Indexed as

AgedAged, 80 and overEmergency Medical ServicesEmergency Service, HospitalFemaleFibrinolytic AgentsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProspective StudiesRegistriesStrokeThrombolytic TherapyFibrinolytic AgentsTissue Plasminogen Activatoremergency medical servicesstrokethrombolytic therapy

Identifiers

PMID24296308
PMCPMC4069247

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.