ArticleTranslational neuroscience2013
NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER.
Article in Translational neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder.The Australian and New Zealand journal of psychiatry · 2015Pooled it
- Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder.The Australian and New Zealand journal of psychiatry · 2015Pooled it
- Psychoneural reduction revised: The case of suicidality in bipolar disorder.The European journal of neuroscience · 2025Review
- Suicide prevention and ketamine: insights from computational modeling.Frontiers in psychiatry · 2023Review
- Cigarette smoking and risk of suicide in bipolar disorder: a systematic review.Frontiers in psychiatry · 2023Review
- Integrating biobehavioral information to predict mood disorder suicide risk.Brain, behavior, & immunity - health · 2022Review
- Review
- A Brain-Centric Model of Suicidal Behavior.The American journal of psychiatry · 2020Article
- Pharmacological Treatment of Bipolar Depression: What are the Current and Emerging Options?Neuropsychiatric disease and treatment · 2020Article
- Familial Aggregation and Coaggregation of Suicide Attempts and Comorbid Mental Disorders in Adults.JAMA psychiatry · 2019Article
- Serotonin receptors and suicide, major depression, alcohol use disorder and reported early life adversity.Translational psychiatry · 2018Article
- ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.NeuroImage · 2017Review
- Existing and novel biological therapeutics in suicide prevention.American journal of preventive medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Suicide and bipolar disorder (BD) are challenging, complex, and intertwined areas of study in contemporary psychiatry. Indeed, BD is associated with the highest lifetime risk for suicide attempt and completion of all the psychiatric conditions. Given that several clinical risk factors for both suicide and BD have been well noted in the literature, exploring the neurobiological aspects of suicide in BD may provide insights into both preventive measures and future novel treatments. This review synthesizes findings regarding the neurobiological aspects of suicide and, when applicable, their link to BD. Neurochemical findings, genes/epigenetics, and potential molecular targets for current or future treatments are discussed. The role of endophenotypes and related proximal and distal risk factors underlying suicidal behavior are also explored. Lastly, we discuss the manner in which preclinical work on aggression and impulsivity may provide additional insights for the future development of novel treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.