Evidence map›Paper›PMID 24294337›Full record

ArticleCognitive neurodynamics2012

Investigation of changes in EEG complexity during memory retrieval: the effect of midazolam.

Nasibeh Talebi, Ali M Nasrabadi, Tim Curran

Open access · bronzeAbstract read
In one paragraph

Article in Cognitive neurodynamics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Entropy of the resting state cortex in epilepsy.Biomedical physics & engineering express · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Nasibeh TalebiDepartment of Biomedical Engineering, Faculty of Engineering, Shahed University, Tehran, Iran.
Ali M Nasrabadi
Tim Curran
Shahed University · IRUniversity of Colorado Boulder · US

Funding

ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI WALDERS, NATALIE · 1985 to 2008
$52.6M
ERP Studies of Dual Processes in Recognition MemoryR01MH064812 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI CURRAN, TIMOTHY E · 2002 to 2011
$3.0M
NCRR NIH HHS M01 RR000051NIMH NIH HHS R01 MH064812
6 · The paper itself

Abstract

The aim of this study is applying nonlinear methods to assess changes in brain dynamics in a placebo-controlled study of midazolam-induced amnesia. Subjects injected with saline and midazolam during study, performed old/new recognition memory tests with EEG recording. Based on previous studies, as midazolam causes anterograde amnesia, we expected that midazolam would affect the EEG's degree of complexity. Recurrence quantification analysis, and approximate entropy were used in this assessment. These methods compare with other nonlinear techniques such as computation of the correlation dimension, are suitable for non-stationary EEG signals. Our findings suggest that EEG's complexity decreases during memory retrieval. Although this trend is observed in nonlinear curves related to the midazolam condition, the overall complexity were greater than in the saline condition. This result implies that impaired memory function caused by midazolam is associated with greater EEG's complexity compared to normal memory retrieval in saline injection.

Indexed as

Approximate entropyERPMemoryNonlinear analysisRecurrence quantification analysis (RQA)

Identifiers

PMID24294337
PMCPMC3495074
OpenAlexW2162816531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.