Evidence map›Paper›PMID 24294307›Full record

ArticleNano LIFE2013

SENSING DNA WITH ALTERNATING CURRENTS USING A NANOGAP SENSOR EMBEDDED IN A NANOCHANNEL DEVICE.

Bret H Davis, Junhan Pan, Chih-Kuan Tung, Robert H Austin, Robert Riehn

Abstract read
In one paragraph

Article in Nano LIFE, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bret H DavisDepartment of Physics, North Carolina State University Campus Box 8202, Raleigh, NC 27695, USA.
Junhan Pan
Chih-Kuan Tung
Robert H Austin
Robert Riehn

Funding

Sequencing DNA by transverse electrical measurements in NanochannelsR21HG004383 · NHGRI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI RIEHN, ROBERT · 2007 to 2009
$541k
NHGRI NIH HHS R21 HG004383
6 · The paper itself

Abstract

We report an integrated nanochannel/nanoelectrode sensor for the detection of DNA using alternating currents. We find that DNA can be detected using platinum as the metal for the detecting electrodes, with a signal to noise ratio exceeding 10. We argue that the signal is at least in part electrochemical in nature, thus holds the promise to yield a sequence-dependent signal. However, we also find that for large voltages, DNA attaches irreversibly to the driving electrodes.

Indexed as

DNA sequencingnanochannelsnanoelectrodes

Identifiers

PMID24294307
PMCPMC3842156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.