ArticleExperimental and clinical cardiology2013
Mitral annulus calcification is independently associated with all-cause mortality.
Article in Experimental and clinical cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification.Journal of the American College of Cardiology · 2017Trial
- Cardiac calcium score on 2D echo: correlations with cardiac and coronary calcium at multi-detector computed tomography.Cardiovascular ultrasound · 2014Trial
- Mitral annular calcification: implications on clinical outcomes and interventions.Annals of cardiothoracic surgery · 2025Review
- Surgical or transcatheter mitral valve replacement with mitral annular calcification.JTCVS structural and endovascular · 2024Article
- Extensive calcification of the mitral valve annulus in transcatheter aortic valve implants.Interactive cardiovascular and thoracic surgery · 2022Article
- Survival of people with valvular heart disease in a large, English community-based cohort study.Heart (British Cardiac Society) · 2021Article
- Mitral valve replacement in mitral stenosis; the problem of small left ventricle.Journal of cardiothoracic surgery · 2020Article
- Surgical mitral valve replacement using direct implantation of Sapien 3 valve in a patients with severe mitral annular calcification without adjunctive techniques, a case report.Journal of cardiothoracic surgery · 2020Review
- Morphological and functional characteristics of mitral annular calcification and their relationship to stroke.PloS one · 2020Article
- Assessment of left atrial volume and mechanical functions using real-time three-dimensional echocardiography in patients with mitral annular calcification.Anatolian journal of cardiology · 2016Article
- Mitral Valve Annuloplasty Ring Dehiscence Diagnosed Intraoperative With Real-Time 3D Transesophageal Echocardiogram.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMitral annulus calcification (MAC) is an important echocardiographic finding that is significantly associated with valvular abnormalities. However, the effect of documented MAC on all-cause mortality is not known. Using a large database, associations between MAC and long-term all-cause mortality were evaluated.
methodsA retrospective analysis of 3169 echocardiograms, which were performed for clinical reasons in southern California between 1983 and 1998 in patients between 16 and 99 years of age, was performed. Mortality data were extracted from the national mortality database at the end of 2007. Using uni- and multivariate analysis, associations between total mortality and the echocardiographic presence of MAC documented in the final report by the interpreting cardiologist were evaluated.
resultsMAC was significantly associated with all-cause mortality (174 of 334 [52.1%] patients with MAC died versus 709 of 2835 [25.0%] patients without MAC; OR 3.26 [95% CI 2.58 to 4.10]; P<0.001). Using multivariate analysis adjusting for age, left ventricular hypertrophy, sex, abnormal left ventricular systolic function and significant valvular abnormalities, MAC remained independently associated with all-cause mortality (OR 2.50 [95% CI 1.81 to 3.45]; P<0.001).
conclusionUsing a large echocardiographic database, MAC was found to be independently associated with all-cause mortality. This finding confirms the importance of an abnormal mitral annulus as an important prognostic marker.
Indexed as
Identifiers
24294050PMC3716491W61151013What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.