ArticleInternational journal of nephrology and renovascular disease2013
Features and outcomes of lupus nephritis in Morocco: analysis of 114 patients.
Article in International journal of nephrology and renovascular disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk of End-Stage Renal Disease in Patients With Lupus Nephritis, 1971-2015: A Systematic Review and Bayesian Meta-Analysis.Arthritis & rheumatology (Hoboken, N.J.) · 2016Pooled it
- Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco.BioMed research international · 2018Trial
- Kidney Biopsy and Prognosis in Lupus Nephritis: Histological Predictors of Renal Outcome-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Treatment outcome and survival status among adult patients treated for lupus nephritis in selected tertiary hospitals of Ethiopia.Scientific reports · 2024Article
- Management practice and treatment outcomes of adult patients with Lupus Nephritis at the Renal Clinic of St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.BMC nephrology · 2022Article
- Article
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Authors and funding
11 authors.
Funding
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Abstract
backgroundThere is wide variation in clinical presentation and outcome of lupus nephritis (LN) among different ethnic groups. Few data for LN exist on North Africans, especially those from Morocco. The aim of our study was to review retrospectively the features and outcome of LN in Moroccan patients. PATIENTS AND
methodsWe performed a single-center retrospective study. A total of 114 patients with LN were included. All patients met American Rheumatism Association criteria. LN was classified according to the International Society of Nephrology/Renal Pathology Society classification. We adopted previously defined outcome criteria for LN.
resultsThere were 101 females and 13 males, with a mean age of 29.9 years. At first presentation, we noted hypertension in 33%, hematuria in 76%, nephrotic syndrome in 53%, and renal failure in 60% of cases. Renal biopsy revealed predominant proliferative classes in more than 80% of patients. Patients received different regimens mainly based on intravenous cyclophosphamide. After a mean follow-up of 22 months, remission occurred in 45.5%, relapses in 82%, end-stage renal failure in 21%, and death in 16% of cases. Infection and neurological and cardiovascular diseases were the most frequent causes of death.
conclusionLN seems to be severe in our study, with a predominance of proliferative forms, severe renal manifestations, and poor renal and overall survival.
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