Evidence map›Paper›PMID 24293110›Full record

ReviewCurrent pain and headache reports2014

Cancer-induced oxidative stress and pain.

Mina G Nashed, Matthew D Balenko, Gurmit Singh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Promising Antioxidant Activity ofInternational journal of molecular sciences · 2020
    Review
  7. Hydroethanolic Stem Bark Extract ofAdvances in pharmacological and pharmaceutical sciences · 2020
    Article
  8. Article
  9. Quercetin reduces Ehrlich tumor-induced cancer pain in mice.Analytical cellular pathology (Amsterdam) · 2015
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mina G NashedDepartment of Pathology & Molecular Medicine, McMaster University, Lab 4 N48 Health Sciences Building, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4 L8, Canada, nashedm@mcmaster.ca.
Matthew D Balenko
Gurmit Singh
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer pain is a well-documented and prevalent healthcare problem, with current treatment strategies often failing to achieve acceptable efficacy. One of the major difficulties in treating cancer pain owes to the complex interplay between the cancer microenvironment, cancer therapy, and the body's own responses to these biochemical changes. A better understanding of the molecular pathways of nociception that are activated during cancer progression and treatment is necessary for better pain management and increased quality of life. This article reviews the current research that implicates oxidative stress as an important target for attenuating cancer pain. Sources of oxidative stress are first established, followed by a discussion of the various pathways that are affected by oxidative stress and that ultimately cause cancer pain.

Indexed as

Oxidative StressAntineoplastic AgentsAntioxidantsDisease ProgressionFemaleGlutamic AcidHumansMaleNeoplasmsNociceptive PainPain ManagementQuality of LifeAntineoplastic AgentsAntioxidantsGlutamic Acid

Identifiers

PMID24293110
OpenAlexW1993767406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.