Evidence map›Paper›PMID 24292873›Full record

Trial reportIntensive care medicine2014

Early postoperative prophylactic noninvasive ventilation after major lung resection in COPD patients: a randomized controlled trial.

Christine Lorut, Aurélie Lefebvre, Benjamin Planquette, Laurent Quinquis, Hervé Clavier, Nicola Santelmo, Halim Abou Hanna, François Bellenot, Jean-François Regnard, Marc Riquet and 6 more

Erratum issued 2 registry-linked trialsOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01845402 completednot on this map

The Prevalence of Chronic Kidney Disease at Adolescence in Patients With Congenital Cardiac Disease, Having Undergone Corrective Surgery During Childhood

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2013 to 2015Enrolled120ConditionsChronic Kidney Failure, Congenital Heart DefectsArmsblood and urine samples
NCT03289611 nacompletednot on this mapstarted 2018, after this paper: background citation

Preeclampsia Ratio (sFlt-1/PlGF) Evaluation for Clinical and Obstetrical Guidance

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2018 to 2020Enrolled84ConditionsPreeclampsiaArmssFlt-1 / PlGF ratio
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Christine LorutService de pneumologie et USIR, Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hôtel-Dieu Hospital Group, Site Cochin, AP-HP, University Paris5, René Descartes, 27 rue du Faubourg Saint Jacques, 75679, Paris cedex 14, France. christine.lorut@cch.aphp.fr.
Aurélie LefebvreService de pneumologie et USIR, Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hôtel-Dieu Hospital Group, Site Cochin, AP-HP, University Paris5, René Descartes, 27 rue du Faubourg Saint Jacques, 75679, Paris cedex 14, France.
Benjamin PlanquetteDepartment of Respiratory and Intensive Care Medicine, European Georges Pompidou Hospital, AP-HP, University Paris5, René Descartes, Paris, France.
Laurent QuinquisDepartment of Biostatistics and Epidemiology, Hôtel-Dieu Hospital, AP-HP, University Paris5, René Descartes, Paris, France.
Hervé ClavierDepartment of intensive care Medicine, Institut Montsouris Hospital, Paris, France.
Nicola SantelmoDepartment of Thoracic Surgery, University Hospital, Strasbourg, France.
Halim Abou HannaDepartment of Thoracic Surgery, University Hospital, Dijon, France.
François BellenotDepartment of Thoracic Surgery, University Hospital, Pontoise, France.
Jean-François RegnardDepartment of Thoracic Surgery, Cochin-Broca-Hôtel-Dieu Hospital Group, AP-HP, University Paris5, René Descartes, Paris, France.
Marc RiquetDepartment of Thoracic Surgery, European Georges Pompidou Hospital, AP-HP, University Paris5, René Descartes, Paris, France.
Pierre MagdeleinatDepartment of Thoracic Surgery, Institut Montsouris Hospital, Paris, France.
Guy MeyerDepartment of Respiratory and Intensive Care Medicine, European Georges Pompidou Hospital, AP-HP, University Paris5, René Descartes, Paris, France.
Nicolas RocheService de pneumologie et USIR, Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hôtel-Dieu Hospital Group, Site Cochin, AP-HP, University Paris5, René Descartes, 27 rue du Faubourg Saint Jacques, 75679, Paris cedex 14, France.
Gérard HuchonService de pneumologie et USIR, Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hôtel-Dieu Hospital Group, Site Cochin, AP-HP, University Paris5, René Descartes, 27 rue du Faubourg Saint Jacques, 75679, Paris cedex 14, France.
Joel CosteDepartment of Biostatistics and Epidemiology, Hôtel-Dieu Hospital, AP-HP, University Paris5, René Descartes, Paris, France.
Antoine RabbatService de pneumologie et USIR, Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hôtel-Dieu Hospital Group, Site Cochin, AP-HP, University Paris5, René Descartes, 27 rue du Faubourg Saint Jacques, 75679, Paris cedex 14, France.
Université Paris Cité · FRInstitute Mutualiste Montsouris · FRAssistance Publique – Hôpitaux de Paris · FRHôtel-Dieu de Paris · FRMaison des Sciences de l’Homme de Dijon · FRUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate whether prophylactic postoperative NIV prevents respiratory complications following lung resection surgery in COPD patients.

methodsIn seven thoracic surgery departments, 360 COPD patients undergoing lung resection surgery were randomly assigned to two groups: conventional postoperative treatment without (n = 179) or with (n = 181) prophylactic NIV, applied intermittently during 6 h per day for 48 h following surgery. The primary endpoint was the rate of acute respiratory events (ARE) at 30 days postoperatively (ITT analysis). Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and duration of ICU and hospital stay. MEASUREMENTS AND MAIN

resultsARE rates did not differ between the prophylactic NIV and control groups (57/181, 31.5 vs. 55/179, 30.7%, p = 0.93). ARF rate was 18.8% in the prophylactic NIV group and 24.5% in controls (p = 0.20). Re-intubation rates were similar in the prophylactic NIV and control group [10/181 (5.5%) and 13/179 (7.2%), respectively, p = 0.53]. Mortality rates were 5 and 2.2% in the control and prophylactic NIV groups, respectively (p = 0.16). Infectious and non-infectious complication rates, and duration of ICU and hospital stays were similar between groups.

conclusionsProphylactic postoperative NIV did not reduce the rate of ARE in COPD patients undergoing lung resection surgery and did not influence other postoperative complications rates, mortality rates, and duration of ICU and hospital stay.

Indexed as

Noninvasive VentilationPneumonectomyFeasibility StudiesFemaleHumansLung DiseasesMaleMiddle AgedPostoperative CarePostoperative ComplicationsProspective StudiesPulmonary Disease, Chronic ObstructiveTime Factors

Identifiers

PMID24292873
OpenAlexW2082552953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.