ReviewTranslational research : the journal of laboratory and clinical medicine2014
Retinal repair with induced pluripotent stem cells.
Review in Translational research : the journal of laboratory and clinical medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 42 citations in OpenAlex.
- Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial.Ophthalmology · 2016Trial
- Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind.Ophthalmology · 2015Trial
- Argus II retinal prosthesis for retinitis pigmentosa in the Middle East: The 2015 Pan-American Association of Ophthalmology Gradle Lecture.International journal of retina and vitreous · 2021Article
- Design and Characterization of Biomimetic Kerateine Aerogel-Electrospun Polycaprolactone Scaffolds for Retinal Cell Culture.Annals of biomedical engineering · 2021Article
- Effect of Stem Cell-Derived Extracellular Vesicles on Damaged Human Corneal Endothelial Cells.Stem cells international · 2021Article
- Assessment of Postoperative Morphologic Retinal Changes by Optical Coherence Tomography in Recipients of an Electronic Retinal Prosthesis Implant.JAMA ophthalmology · 2019Article
- Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells.Scientific reports · 2018Article
- Regenerating Eye Tissues to Preserve and Restore Vision.Cell stem cell · 2018Review
- Managing Bardet-Biedl Syndrome-Now and in the Future.Frontiers in pediatrics · 2018Review
- Effects of RPE-conditioned medium on the differentiation of hADSCs into RPE cells, and their proliferation and migration.Experimental and therapeutic medicine · 2017Article
- Roles of exosomes in the normal and diseased eye.Progress in retinal and eye research · 2017Review
- Transitional Progenitors during Vertebrate Retinogenesis.Molecular neurobiology · 2017Review
- Development of the Ultra-Low Vision Visual Functioning Questionnaire (ULV-VFQ).Translational vision science & technology · 2017Article
- Generation of Retinal Progenitor Cells from Human Induced Pluripotent Stem Cell-Derived Spherical Neural Mass.Tissue engineering and regenerative medicine · 2017Article
- Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage.Stem cells translational medicine · 2016Article
- Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells: Applications for the Study and Treatment of Optic Neuropathies.Current ophthalmology reports · 2015Article
- Atoh7 promotes the differentiation of Müller cells-derived retinal stem cells into retinal ganglion cells in a rat model of glaucoma.Experimental biology and medicine (Maywood, N.J.) · 2015Article
- Current focus of stem cell application in retinal repair.World journal of stem cells · 2015Review
- Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Photoreceptor ablation initiates the immediate loss of glutamate receptors in postsynaptic bipolar cells in retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Retinal degeneration such as age-related macular degeneration and other inherited forms, such as Stargardt's disease and retinitis pigmentosa, and optic neuropathies including glaucoma and ischemic optic neuropathy are major causes of vision loss and blindness worldwide. Damage to retinal pigment epithelial cells and photoreceptors in the former, and to retinal ganglion cell axons in the optic nerve and their cell bodies in the retina in the latter diseases lead to the eventual death of these retinal cells, and in humans there is no endogenous replacement or repair. Cell replacement therapies provide 1 avenue to restore function in these diseases, particularly in the case of retinal repair, although there are considerable issues to overcome, including the differentiation and integration of the transplanted cells. What stem cell sources could be used for such therapies? One promising source is induced pluripotent stem cells (iPSCs), which could be drawn from an individual patient needing therapy, or generated and banked from select donors. We review developing research in the use of iPSCs for retinal cell replacement therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.