Evidence map›Paper›PMID 24290805›Full record

ArticleOphthalmology2014

Driving habits in older patients with central vision loss.

Sabyasachi Sengupta, Suzanne W van Landingham, Sharon D Solomon, Diana V Do, David S Friedman, Pradeep Y Ramulu

Abstract readComparative Study
In one paragraph

Article in Ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Visual Impairment and Driving in Older Adults: A Narrative Review.Current treatment options in neurology · 2026
    Review
  4. Article
  5. Article
  6. Development and Validation of a Novel Night-Time Hazard Visibility Test.Translational vision science & technology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Age-Related Diseases and Driving Safety.Geriatrics (Basel, Switzerland) · 2020
    Review
  18. The Mind Cannot Go Blind: Effects of Central Vision Loss on Judging One's Crossing Time.Optometry and vision science : official publication of the American Academy of Optometry · 2020
    Article
  19. Article
  20. Effects of Age-Related Macular Degeneration on Driving Performance.Investigative ophthalmology & visual science · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sabyasachi SenguptaWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland.
Suzanne W van LandinghamWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland.
Sharon D SolomonWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland.
Diana V DoWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland.
David S FriedmanWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland.
Pradeep Y RamuluWilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland. Electronic address: pramulu1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Optimizing Safety and Functionality in the Visually ImpairedR01EY022976 · NEI · JOHNS HOPKINS UNIVERSITY · PI RAMULU, PRADEEP YAMMANURU · 2013 to 2024
$5.2M
Direct evaluation of functional impairment in glaucoma.K23EY018595 · NEI · JOHNS HOPKINS UNIVERSITY · PI RAMULU, PRADEEP YAMMANURU · 2009 to 2012
$876k
NCATS NIH HHS UL1 TR001079NEI NIH HHS EY018595NEI NIH HHS K23 EY018595NEI NIH HHS R01 EY022976
6 · The paper itself

Abstract

objectiveTo determine if central visual loss is associated with driving cessation, driving restriction, or other-driver preference.

designCross-sectional study.

participantsSixty-four subjects with bilateral visual loss (<20/32 in better eye) or severe unilateral visual loss (<20/200) from age-related macular degeneration (AMD) and 58 normally sighted controls between 60 and 80 years of age.

methodsParticipants self-reported driving habits. Other-driver preference was defined as preferring that another drive when there is more than 1 driver in the car. Subjects reporting 2 or more driving limitations were considered to have restricted their driving.

main outcome measuresSelf-reported driving cessation, other-driver preference, and driving restriction.

resultsAge-related macular degeneration subjects were older (74.7 vs. 69.7 years), had worse visual acuity (VA; mean better-eye VA, 0.43 vs. 0.08 logarithm of minimum angle of resolution [logMAR]) and contrast sensitivity (CS; 1.4 vs. 1.9 log units of CS [logCS]), and were more likely to be white when compared with controls (P<0.001 for all). Drivers with AMD-related vision loss were more likely to avoid driving over longer distances, beyond 1 hour, at night, and in unfamiliar conditions (P < 0.05 for all). In multivariate models, driving cessation was associated with worse better-eye VA (odds ratio [OR], 1.5 per 1-line decrement in VA; P<0.001) and worse binocular CS (OR, 1.36 per 0.1 logCS increment; P = 0.005); however, AMD group status was not associated with driving cessation (OR, 1.9; P = 0.35). Factors predicting driving restriction were AMD (OR, 9.0; P = 0.004), worse vision (OR, 2.5 per line of VA loss; P<0.001), lower CS (OR, 2.2 per 0.1-logCS increment; P<0.001), and female gender (OR, 27.9; P = 0.002). Other-driver preference was more common with worse vision (OR, 1.6 per 0.1-logMAR increment; P = 0.003), female gender (OR, 4.5; P = 0.02), and being married (OR, 3.8; P = 0.04).

conclusionsMost patients with AMD-related central vision loss continue to drive, but demonstrate significant driving restrictions, especially with more severe VA and CS loss. Future work should determine which driving adaptations the visually impaired best balance safety and independence.

Indexed as

Adaptation, PhysiologicalAgedAutomobile DrivingContrast SensitivityCross-Sectional StudiesFemaleHumansMacular DegenerationMaleMarylandPersons with Visual DisabilitiesSurveys and QuestionnairesVision, LowVisual Acuity

Identifiers

PMID24290805
PMCPMC3943660
OpenAlexW2077527231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.