Evidence map›Paper›PMID 24290748›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2014

Anesthetic considerations for thoracoscopic sympathetic ganglionectomy to treat ventricular tachycardia storm: a single-center experience.

Emily Methangkool, Jason H Chua, Anupama Gopinath, Kalyanam Shivkumar, Aman Mahajan

Abstract read
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Sedation in the Electrophysiology Laboratory: A Multidisciplinary Review.Journal of the American Heart Association · 2016
    Review
  5. Review
  6. Innervation of the heart: An invisible grid within a black box.Trends in cardiovascular medicine · 2016 · on this map
    Review
  7. Cardiac Syndrome X: update 2014.Cardiology clinics · 2014
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emily MethangkoolDepartments of *Anesthesiology and.
Jason H ChuaSurgery.
Anupama GopinathSurgery.
Kalyanam ShivkumarCardiac Arrhythmia Center, David Geffen School of Medicine at the University of California Los Angeles, CA.
Aman MahajanDepartments of *Anesthesiology and. Electronic address: amahajan@mednet.ucla.edu.
University of California, Los Angeles · US

Funding

ELECTROPHYSIOLOGICAL EFFECTS OF NEURAL REMODELING OF THE VENTRICLESR01HL084261 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM · 2006 to 2016
$3.4M
NHLBI NIH HHS R01 HL084261
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine the pertinent anesthetic considerations for patients undergoing surgical sympathectomy for electrical storm (incessant ventricular tachycardia (VT) refractory to traditional therapies).

designThis is a retrospective review of a prospective database.

settingThis single-center study took place in a university hospital setting.

participantsTwenty-six patients were enrolled.

interventionsFifteen patients underwent left-sided sympathectomy, whereas 11 patients underwent bilateral sympathectomy. MEASUREMENTS AND MAIN

resultsAnesthetic management of these patients was quite complex, requiring invasive monitoring, transesophageal echocardiography, one-lung ventilation, programming of cardiac rhythm management devices, and titration of vasoactive medications. Paired t test of hemodynamic data before, during, and after surgery showed no significant difference between preoperative and postoperative blood pressure values, regardless of whether the patient underwent unilateral or bilateral sympathectomy. Eight patients remained free of VT, three patients responded well to titration of oral medications, and one patient required 2 radiofrequency ablations after sympathectomy to control his VT. Three patients continued to have VT episodes, although reduced in frequency compared with before the procedure. Four patients were lost to followup. Overall, five patients within the cohort died within 30 days of the procedure. No patients developed any anesthetic complications or Horner's syndrome. The overall perioperative mortality (within the first 7 days of the procedure) was 2 of 26, or 7.7%.

conclusionsThe anesthetic management of patients undergoing surgical sympathectomy for electrical storm can be quite complex, because these patients often present in a moribund and emergent state and cannot be optimized using current ACC/AHA guidelines. Expertise in invasive monitoring, transesophageal echocardiography, one-lung ventilation, cardiac rhythm device management, and pressor management is crucial for optimal anesthetic care.

Indexed as

AgedAnesthesiaEchocardiography, TransesophagealFemaleGanglia, SympatheticGanglionectomyHumansMaleMiddle AgedRetrospective StudiesTachycardia, VentricularThoracoscopyelectrical stormstellate ganglionectomysympathectomyventricular tachycardia

Identifiers

PMID24290748
PMCPMC4253028
OpenAlexW1969574146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.