Evidence map›Paper›PMID 24290365›Full record

ArticleDeutsches Arzteblatt international2013

The febrile child: diagnosis and treatment.

Tim Niehues

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Additional comments regarding diagnosis and treatment.Deutsches Arzteblatt international · 2014
    Article
  13. Economicalness of outpatient laboratory diagnostics.Deutsches Arzteblatt international · 2014
    Article
  14. Do not administer free glucose solution.Deutsches Arzteblatt international · 2014
    Article
  15. Laboratory tests are important.Deutsches Arzteblatt international · 2014
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  16. Pointers for the examination technique.Deutsches Arzteblatt international · 2014
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  17. Consider further differential diagnoses.Deutsches Arzteblatt international · 2014
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  18. In reply.Deutsches Arzteblatt international · 2014
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Tim NiehuesCentre for Pediatric and Adolescent Medicine, HELIOS Klinikum Krefeld.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFever accounts for 70% of all consultations with pediatricians and family physicians. Fever without an identifiable cause (<7 days' duration) and fever of unknown origin (FUO, ≥ 7 days' duration) are particularly challenging clinical situations.

methodThis article is based on a selective literature search for publications containing the term "pediatric fever management," with special attention to meta-analyses and systematic reviews.

resultsThe mainstay of diagnosis is physical examination by a physician who is experienced in the care of children and adolescents. The frequency of severe bacterial infection (SBI) is about 10% in neonates, 5% in babies aged up to 3 months, and 0.5% to 1% in older infants and toddlers. The mortality of SBI in neonates is about 10%. Both the degree of the parents' and the physician's concern are important warning signs for SBI. Clinical signs of SBI include cyanosis, tachypnea, poor peripheral perfusion, petechiae, and a rectal temperature above 40°C. Antipyretic drugs should only be used in special, selected situations. More than 40% of cases of FUO are due to infection; in more than 30% of cases, the cause is never determined.

conclusionAspects of central importance include the repeated physical examination of the patient, and parent counseling and education of medical and nursing staff pertaining to the warning signs for SBI. Research is needed in the areas of diagnostic testing and the development of new vaccines.

Indexed as

Evidence-Based MedicineBacterial InfectionsCausalityChildChild, PreschoolComorbidityDiagnosis, DifferentialFemaleFever of Unknown OriginHumansInfantInfant, NewbornMalePhysical ExaminationPrevalenceRisk Assessment

Identifiers

PMID24290365
PMCPMC3849992

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.