ReviewThe Journal of allergy and clinical immunology2014
Asthma across the ages: knowledge gaps in childhood asthma.
Review in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Association between active tobacco use during pregnancy and infant respiratory health: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation.The journal of allergy and clinical immunology. In practice · 2019Trial
- Individualized therapy for persistent asthma in young children.The Journal of allergy and clinical immunology · 2016Trial
- Prevalence of uncontrolled childhood asthma and its association with parental knowledge in Karachi, Pakistan.BMJ paediatrics open · 2026Article
- Molecular mechanism ofSaudi journal of biological sciences · 2023Article
- Delayed acquisition of airway commensals in antibiotic naïve children and its relationship with wheezing in rural Ecuador.Frontiers in allergy · 2023Article
- Pre-eclampsia and risk of early-childhood asthma: a register study with sibling comparison and an exploration of intermediate variables.International journal of epidemiology · 2022Article
- Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic-Pituitary-Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.Child development · 2021Article
- Cellular Therapy for the Treatment of Paediatric Respiratory Disease.International journal of molecular sciences · 2021Review
- Article
- Influence of exhaled breath condensates from children with asthma on endothelial cells culturedPostepy dermatologii i alergologii · 2020Article
- Heterogeneity of Mild to Moderate Persistent Asthma in Children: Confirmation by Latent Class Analysis and Association with 1-Year Outcomes.The journal of allergy and clinical immunology. In practice · 2020Article
- Pediatric asthma: An unmet need for more effective, focused treatments.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2019Review
- [Patients with cystic fibrosis become adults : Treatment hopes and disappointments].Der Internist · 2019Review
- Severe Asthma-Perspectives From Adult and Pediatric Pulmonology.Frontiers in pediatrics · 2019Review
- Clinical efficacy and safety of anticholinergic therapies in pediatric patients.Therapeutics and clinical risk management · 2019Review
- Ma Huang Tang ameliorates bronchial asthma symptoms through the TLR9 pathway.Pharmaceutical biology · 2018Article
- Serum Clara cell protein and atopic phenotype in children up to 2 years of age.Journal of clinical laboratory analysis · 2017Article
- Spatiotemporal patterns of childhood asthma hospitalization and utilization in Memphis Metropolitan Area from 2005 to 2015.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017Article
- Sputum pentraxin 3 as a candidate to assess airway inflammation and remodeling in childhood asthma.Medicine · 2016Article
Corrections and comments
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Authors and funding
9 authors at 9 institutions in 2 countries.
Funding
Abstract
The Eunice Kennedy Shriver National Institute of Child Health and Human Development convened an Asthma Group in response to the Best Pharmaceuticals for Children Act. The overall goal of the Best Pharmaceuticals for Children Act Program is to improve pediatric therapeutics through preclinical and clinical drug trials that lead to drug-labeling changes. Although significant advances have been made in the understanding and management of asthma in adults with appropriately labeled medications, less information is available on the management of asthma in children. Indeed, many medications are inadequately labeled for use in children. In general, the younger the child, the less information there is available to guide clinicians. Because asthma often begins in early childhood, it is incumbent on us to continue to address the primary questions raised in this review and carefully evaluate the medications used to manage asthma in children. Meanwhile, continued efforts should be made in defining effective strategies that reduce the risk of exacerbations. If the areas of defined need are addressed in the coming years, namely prevention of exacerbations and progression of disease, as well as primary intervention, we will see continuing reduction in asthma mortality and morbidity along with improved quality of life for children with asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.