ReviewArthritis research & therapy2013
Beyond pain in fibromyalgia: insights into the symptom of fatigue.
Review in Arthritis research & therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Effect of photobiomodulation on pain and quality of life in fibromyalgia syndrome: a systematic review.Lasers in medical science · 2026Pooled it
- Cluster analysis in fibromyalgia: a systematic review.Rheumatology international · 2024Pooled it
- Evaluation of viral infection as an etiology of ME/CFS: a systematic review and meta-analysis.Journal of translational medicine · 2023Pooled it
- A randomized comparative feasibility study of neuromodulation and cognitive training for post-COVID fatigue.Scientific reports · 2025Trial
- Emerging Clinical Technology: Application of Machine Learning to Chronic Pain Assessments Based on Emotional Body Maps.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Trial
- Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial.Arthritis research & therapy · 2016Trial
- Self-Reported Symptom Burden and Clinical Characteristics in Fibromyalgia: Evidence from a Large Online Survey in Italy.Medicina (Kaunas, Lithuania) · 2026Article
- Article
- Healthcare providers' perceptions of fibromyalgia management in Kuwait: a descriptive comparative study.BMC health services research · 2026Article
- How am I doing? It varies: mixed-effects location scale modeling to examine intra-individual variability in health-related research.Journal of behavioral medicine · 2026Article
- Screening and Management of Sleep Disorders in Patients with Fibromyalgia Syndrome: A French Multicenter, Prospective, Observational Study.Pain and therapy · 2026Article
- The Gür fibromyalgia model: a clinically operational framework for phenotype-informed, sequence-sensitive multimodal care.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Evaluation of reserpine-induced fibromyalgia in mice: A comparative behavioral, neurochemical, and histological assessment of two doses.IBRO neuroscience reports · 2025Article
- Evaluation of minimum pinch force while holding in fibromyalgia patients.Irish journal of medical science · 2025Article
- Psychosocial Correlates of Fatigue in Young Adults with Multiple Sclerosis: Exploring the Roles of Resilience, Mindfulness, and Illness Perception.Healthcare (Basel, Switzerland) · 2025Article
- Association of Genetic Variants, Such as the μ-Opioid Receptor 1 (Biomedicines · 2025Article
- Review
- A Comprehensive Analysis of Fibromyalgia and the Role of the Endogenous Opioid System.Biomedicines · 2025Review
- Exploring patient activation and self-management experiences in adults with fibromyalgia: a qualitative evidence synthesis.Rheumatology advances in practice · 2025Review
- How Does Conditioned Pain Modulation Influence Motor Imagery Processes in Women with Fibromyalgia Syndrome? A Cross-Sectional Study Secondary Analysis.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Fatigue is a disabling, multifaceted symptom that is highly prevalent and stubbornly persistent. Although fatigue is a frequent complaint among patients with fibromyalgia, it has not received the same attention as pain. Reasons for this include lack of standardized nomenclature to communicate about fatigue, lack of evidence-based guidelines for fatigue assessment, and a deficiency in effective treatment strategies. Fatigue does not occur in isolation; rather, it is present concurrently in varying severity with other fibromyalgia symptoms such as chronic widespread pain, unrefreshing sleep, anxiety, depression, cognitive difficulties, and so on. Survey-based and preliminary mechanistic studies indicate that multiple symptoms feed into fatigue and it may be associated with a variety of physiological mechanisms. Therefore, fatigue assessment in clinical and research settings must consider this multi-dimensionality. While no clinical trial to date has specifically targeted fatigue, randomized controlled trials, systematic reviews, and meta-analyses indicate that treatment modalities studied in the context of other fibromyalgia symptoms could also improve fatigue. The Outcome Measures in Rheumatology (OMERACT) Fibromyalgia Working Group and the Patient Reported Outcomes Measurement Information System (PROMIS) have been instrumental in propelling the study of fatigue in fibromyalgia to the forefront. The ongoing efforts by PROMIS to develop a brief fibromyalgia-specific fatigue measure for use in clinical and research settings will help define fatigue, allow for better assessment, and advance our understanding of fatigue.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.