Trial reportTrials2013
A community-based intervention for primary prevention of cardiovascular diseases in the slums of Nairobi: the SCALE UP study protocol for a prospective quasi-experimental community-based trial.
Trial report in Trials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of hypertension in Ghanaian society: a systematic review, meta-analysis, and GRADE assessment.Systematic reviews · 2021Pooled it
- Evaluating the outcomes of a community-based health literacy intervention for hypertension and diabetes in Harare, Zimbabwe: a cluster randomized controlled trial.BMC primary care · 2026Trial
- Data Resource Profile: Multimorbidity in Africa Digital Innovation, Visualisation and Application (MADIVA) research hub.International journal of epidemiology · 2026Article
- When women win, we all win-Call for a gendered global NCD agenda.FASEB bioAdvances · 2022Review
- Blood Pressure and Blood Glucose Control and Associated Factors Among Adults with Hypertension at Three Public Hospitals in Southern Ethiopia.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022Article
- Target women: Equity in access to mHealth technology in a non-communicable disease care intervention in Kenya.PloS one · 2019Article
- Prevalence of obesity, hypertension, and diabetes, and cascade of care in sub-Saharan Africa: a cross-sectional, population-based study in rural and urban Malawi.The lancet. Diabetes & endocrinology · 2018Article
- Regional and Sex Differences in the Prevalence and Awareness of Hypertension: An H3Africa AWI-Gen Study Across 6 Sites in Sub-Saharan Africa.Global heart · 2017Article
- How does poverty affect children's nutritional status in Nairobi slums? A qualitative study of the root causes of undernutrition.Public health nutrition · 2017Article
- Outcomes and costs of implementing a community-based intervention for hypertension in an urban slum in Kenya.Bulletin of the World Health Organization · 2016Article
- Impact evaluation of a community-based intervention for prevention of cardiovascular diseases in the slums of Nairobi: the SCALE-UP study.Global health action · 2016Article
- Interlinkage among cardio-metabolic disease markers in an urban poor setting in Nairobi, Kenya.Global health action · 2016Article
- Results of a hypertension and diabetes treatment program in the slums of Nairobi: a retrospective cohort study.BMC health services research · 2015Article
- Profile of people with hypertension in Nairobi's slums: a descriptive study.Globalization and health · 2015Article
- Cardiovascular prevention model from Kenyan slums to migrants in the Netherlands.Globalization and health · 2015Article
- A community-based cluster randomized survey of noncommunicable disease and risk factors in a peri-urban shantytown in Lima, Peru.BMC international health and human rights · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe burden of cardiovascular disease is rising in sub-Saharan Africa with hypertension being the main risk factor. However, context-specific evidence on effective interventions for primary prevention of cardiovascular diseases in resource-poor settings is limited. This study aims to evaluate the feasibility and cost-effectiveness of one such intervention--the "Sustainable model for cardiovascular health by adjusting lifestyle and treatment with economic perspective in settings of urban poverty". METHODS/
design
designA prospective quasi-experimental community-based intervention study.
settingTwo slum settlements (Korogocho and Viwandani) in Nairobi, Kenya. STUDY POPULATION: Adults aged 35 years and above in the two communities.
interventionThe intervention community (Korogocho) will be exposed to an intervention package for primary prevention of cardiovascular disease that comprises awareness campaigns, household screening for cardiovascular diseases risk factors, and referral and treatment of people with high cardiovascular diseases risk at a primary health clinic. The control community (Viwandani) will continue accessing the usual standard of care for primary prevention of cardiovascular diseases in Kenya. DATA: Demographic and socioeconomic data; anthropometric and clinical measurements including blood pressure. Population-based data will be collected at the baseline and endline--12 months after implementing the intervention. These data will be collected from a random sample of 1,610 adults aged 35 years and above in the intervention and control sites at both baseline and endline. Additionally, operational (including cost) and clinic-based data will be collected on an ongoing basis. MAIN OUTCOMES: (1) A positive difference in the change in the proportion of the intervention versus control study populations that are at moderate or high risk of cardiovascular disease; (2) a difference in the change in mean systolic blood pressure in the intervention versus control study populations; (3) the net cost of the complete intervention package per disability-adjusted life year gained. ANALYSIS: Primary outcomes comparing pre- and post-, and operational data will be analyzed descriptively and "impact" of the intervention will be calculated using double-difference methods. We will also conduct a cost-effectiveness analysis of the intervention using World Health Organization guidelines. DISCUSSION: The outcomes of the study will be disseminated to local policy makers and health planners.
trial registrationCurrent controlled trials ISRCTN84424579.
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