Evidence map›Paper›PMID 24289689›Full record

ArticlePhysical review letters2013

Ultrasonically encoded photoacoustic flowgraphy in biological tissue.

Lidai Wang, Jun Xia, Junjie Yao, Konstantin I Maslov, Lihong V Wang

Abstract read
In one paragraph

Article in Physical review letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Systematic imaging in medicine: a comprehensive review.European journal of nuclear medicine and molecular imaging · 2021
    Review
  6. Article
  7. Article
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  13. Article
  14. Roadmap on neurophotonics.Journal of optics (2010) · 2016
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lidai WangDepartment of Biomedical Engineering, Optical Imaging Laboratory, Washington University in Saint Louis Campus Box 1097, One Brookings Drive, Saint Louis, Missouri 63130-4899, USA.
Jun Xia
Junjie Yao
Konstantin I Maslov
Lihong V Wang
Washington University in St. Louis · US

Funding

Task Specific Project 3: Diffuse Optical TomographyU54CA136398 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2008 to 2012
$6.0M
PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
PHOTOACOUSTIC MICROSCOPY OF NEOVASCULARIZATION IN RENAL CANCER GROWTH AND THERAPYR01CA159959 · NCI · WASHINGTON UNIVERSITY · PI ARBEIT, JEFFREY MICHAEL · 2011 to 2015
$2.9M
Monitoring of Breast Neoadjuvant Therapy by Thermo- and Photo- Acoustic TomographR01CA134539 · NCI · WASHINGTON UNIVERSITY · PI MONSEES, BARBARA, WANG, LIHONG · 2009 to 2013
$2.9M
Photoacoustic endoscopy of Barretts esophagusR01CA157277 · NCI · WASHINGTON UNIVERSITY · PI MEYERS, BRYAN F, ZHOU, QIFA · 2010 to 2014
$2.7M
RECOVERY OF OPTICAL ABSORPTION COEFFICIENT IN QUANTITATIVE PHOTOACOUSTIC IMAGINGR01EB008085 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2008 to 2011
$2.4M
NCCDPHP CDC HHS DP1 EB016986NCI NIH HHS R01 CA134539NCI NIH HHS R01 CA157277NCI NIH HHS R01 CA159959NCI NIH HHS U54 CA136398NIBIB NIH HHS DP1 EB016986NIBIB NIH HHS R01 EB008085
6 · The paper itself

Abstract

Blood flow speed is an important functional parameter. Doppler ultrasound flowmetry lacks sufficient sensitivity to slow blood flow (several to tens of millimeters per second) in deep tissue. To address this challenge, we developed ultrasonically encoded photoacoustic flowgraphy combining ultrasonic thermal tagging with photoacoustic imaging. Focused ultrasound generates a confined heat source in acoustically absorptive fluid. Thermal waves propagate with the flow and are directly visualized in pseudo color using photoacoustic computed tomography. The Doppler shift is employed to calculate the flow speed. This method requires only acoustic and optical absorption, and thus is applicable to continuous fluid. A blood flow speed as low as 0.24  mm·s(-1)} was successfully measured. Deep blood flow imaging was experimentally demonstrated under 5-mm-thick chicken breast tissue.

Indexed as

BloodHumansLaser-Doppler FlowmetryModels, TheoreticalPhotoacoustic TechniquesUltrasonography, Doppler

Identifiers

PMID24289689
PMCPMC3895050
OpenAlexW2058710820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.