Evidence map›Paper›PMID 24288948›Full record

Trial reportJournal of health, population, and nutrition2013

Protective effect of fish oil supplementation on DNA damage induced by cigarette smoking.

Amir Ghorbanihaghjo, Javid Safa, Samira Alizadeh, Hassan Argani, Nadereh Rashtchizadeh, Mohammad Vahid Taghinia, Mehran Mesgari Abbasi

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of health, population, and nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amir GhorbanihaghjoBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Javid Safa
Samira Alizadeh
Hassan Argani
Nadereh Rashtchizadeh
Mohammad Vahid Taghinia
Mehran Mesgari Abbasi
Tabriz University of Medical Sciences · IRBiotechnology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study examined the influence of fish oil (FO) supplementation on serum 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels as indicated by DNA damage markers and total antioxidant capacity (TAC) among male cigarette smokers. This double-blind, placebo-controlled randomized study was conducted among healthy cigarette smokers (n=40) who were part of a larger prospective cohort study. Twenty smokers were randomly selected to receive FO for 3 months (1 g/day), and another 20 smokers received a placebo for 3 months; 8-OHdG and TAC levels were measured in blood samples before and after the intervention. Serum 8-OHdG significantly decreased (p=0.001) and TAC increased (p<0.001) after 3 months of treatment with FO. Between baseline and endline, the difference in 8-OHdG significantly correlated with the difference in TAC among smokers who received FO (r=-0.540, p=0.014). The study provides evidence that FO supplementation can modify decreased antioxidants and increased oxidative DNA damage in cigarette smokers.

Indexed as

Dietary Supplements8-Hydroxy-2'-DeoxyguanosineAdultAntioxidantsBiomarkersCohort StudiesDeoxyguanosineDNA DamageDouble-Blind MethodFish OilsFollow-Up StudiesHumansMaleProspective StudiesSmoking8-Hydroxy-2'-DeoxyguanosineAntioxidantsBiomarkersDeoxyguanosineFish Oils

Identifiers

PMID24288948
PMCPMC3805884
OpenAlexW2112811811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.