Evidence map›Paper›PMID 24288586›Full record

ArticleJournal of bioanalysis & biomedicine2011

Analysis of House Dust and Children's Hair for Pesticides: A Comparison of Markers of Ongoing Pesticide Exposure in Children.

Enrique M Ostrea, Esterlita Villanueva-Uy, Dawn Bielawski, Sarah Birn, James J Janisse

Open access · greenAbstract read
In one paragraph

Article in Journal of bioanalysis & biomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Enrique M OstreaDepartment of Pediatrics, Hutzel Women's Hospital, the Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA.
Esterlita Villanueva-Uy
Dawn Bielawski
Sarah Birn
James J Janisse
Hutzel Women's Hospital · US

Funding

Fetal exposure to environmental toxins &infant outcomeR01HD039428 · NICHD · WAYNE STATE UNIVERSITY · PI OSTREA, ENRIQUE MAPUA · 2002 to 2012
$5.4M
NICHD NIH HHS R01 HD039428
6 · The paper itself

Abstract

BACKGROUND/

aimThe long term study of the adverse effects of pesticides on child neuro development requires monitoring not only of initial, but ongoing pesticide exposure. Our aim was to compare house dust and children's hair as environmental and biological markers of ongoing pesticide exposure in children. DESIGN/

methodsIn a continuing NIH study on the adverse effects of prenatal pesticide exposure on child neurodevelopment, ongoing pesticide exposure after birth was measured in swept house dust and hair in the children at 4 years of age for propoxur and pyrethroids (transfluthrin, bioallethrin, cyfluthrin and cypermethrin) by gas chromatography/mass spectrometry. The prevalence and concentration of pesticides in the two matrices were compared.

resultsPrevalence of propoxur was higher in hair compared to house dust (p<0.001) whereas prevalence of the pyrethroids was higher (p<0.001) in house dust. The overall concentrations of the pyrethroids were also higher (p<0.007) in house dust compared to hair. There was a significant (p<0.001) correlation between dust and hair for bioallethrin and cypermethrin.

conclusionsOngoing exposure of children to environmental pesticides is sensitively detected by analysis of children's hair and house dust. However, prevalence of propoxur was higher in hair compared to swept house dust, but the opposite was found for the pyrethroids. Thus, both matrices should be analyzed. There was a significant (p<0.001) correlation between house dust and hair for bioallethrin and cypermethrin.

Indexed as

BiomarkersEnvironmental exposureHairHouse dustPesticides

Identifiers

PMID24288586
PMCPMC3840167
OpenAlexW2120346949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.