ArticleVirus genes2014
Molecular characterization and phylogenetic study of velogenic Newcastle disease virus isolates in Iran.
Article in Virus genes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Molecular Identification and Phylogenetic Study Based on the Fusion Gene of Newcastle Disease Virus Isolated from Broiler Poultry Farms in Markazi Province, Iran.Archives of Razi Institute · 2023Article
- The role of Newcastle Disease Virus in Broiler Chickens with High Mortality of Kerman Province.Archives of Razi Institute · 2023Article
- Investigation of Newcastle Disease Virus Infection in Pet Birds in the Southwest of Iran.Archives of Razi Institute · 2023Article
- Characterization of Newcastle disease virus in broiler flocks with respiratory symptoms in some provinces of Iran.Molecular biology reports · 2021Article
- Predominance of Fourth Panzootic Newcastle Disease Virus Subgenotype VII.1.1 in Iran and Its Relation to the Genotypes Circulating in the Region.Current microbiology · 2021Article
- Hemagglutinin-neuraminidase Sequence and Phylogenetic Analysis of Two Newcastle Disease Virus Isolated from Chickens in Iran.Archives of Razi Institute · 2021Article
- Development of a reverse-transcription recombinase polymerase amplification assay with a lateral flow assay for rapid detection of avian orthoavulavirus 1.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Reverse Genetics Assembly of Newcastle Disease Virus Genome Template Using Asis-Sal-Pac BioBrick Strategy.Biological procedures online · 2020Article
- Molecular characterization of haemagglutinin-neuraminidase gene among virulent Newcastle disease viruses isolated in Iran.Iranian journal of veterinary research · 2019Article
- An active serological survey of antibodies to newcastle disease and avian influenza (H9N2) viruses in the unvaccinated backyard poultry in Bushehr province,Iran, 2012-2013.Asian Pacific journal of tropical biomedicine · 2014Article
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7 authors.
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Abstract
The pathogenicity and genetic characterizations of six Newcastle disease virus (NDV) isolates obtained from chicken farms in six different regions in Iran were carried out using conventional and molecular techniques. Based on the pathogenicity indices (MDT, ICPI, and IVPI), all of these isolates were found to be velogenic (highly virulent) strains. A sequence analysis of the full-length mRNA encoding the fusion glycoprotein precursor (F0) of the NDV's fusion proteins F1 and F2 in these six isolates showed the presence of point mutations in form of nucleic acid substitutions at positions 82((C→T)), 83((T→C)), 736((A→G)), and 1,633((G→A)). However, the nucleic acid residues at positions 330-347 of the precursor F0 gene, corresponding to the cleavage site of the F0 protein, were found to have remained conserved among the six NDV isolates. A phylogenetic comparison between the six Iranian isolates and the NDVs whose F0 gene sequences were previously deposited in GenBank Database showed that all of the newly characterized Iranian NDV isolates belonged to genotype VII.
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