Evidence map›Paper›PMID 24287913›Full record

ReviewInternational journal of molecular sciences2013

Regenerative medicine for epilepsy: from basic research to clinical application.

Takao Yasuhara, Takashi Agari, Masahiro Kameda, Akihiko Kondo, Satoshi Kuramoto, Meng Jing, Tatsuya Sasaki, Atsuhiko Toyoshima, Susumu Sasada, Kenichiro Sato and 7 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Takao YasuharaDepartment of Neurological Surgery, Okayama University Graduate School of Medicine, 2-5-1, Shikata-cho, Okayama 700-8558, Japan. tyasu37@cc.okayama-u.ac.jp.
Takashi Agari
Masahiro Kameda
Akihiko Kondo
Satoshi Kuramoto
Meng Jing
Tatsuya Sasaki
Atsuhiko Toyoshima
Susumu Sasada
Kenichiro Sato
Aiko Shinko
Takaaki Wakamori
Yu Okuma
Yasuyuki Miyoshi
Naoki Tajiri
Cesario V Borlongan
Isao Date

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is a chronic neurological disorder, which presents with various forms of seizures. Traditional treatments, including medication using antiepileptic drugs, remain the treatment of choice for epilepsy. Recent development in surgical techniques and approaches has improved treatment outcomes. However, several epileptic patients still suffer from intractable seizures despite the advent of the multimodality of therapies. In this article, we initially provide an overview of clinical presentation of epilepsy then describe clinically relevant animal models of epilepsy. Subsequently, we discuss the concepts of regenerative medicine including cell therapy, neuroprotective agents, and electrical stimulation, which are reviewed within the context of our data.

Indexed as

Regenerative MedicineAnimalsBrain-Derived Neurotrophic FactorCell- and Tissue-Based TherapyElectric StimulationEpilepsyHumansNeural Stem CellsNeuroprotective AgentsBrain-Derived Neurotrophic FactorNeuroprotective Agents

Identifiers

PMID24287913
PMCPMC3876052

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.